The Modulation of the Startle Reflex as Predictor of Alcohol Use Disorders in a Sample of Heavy Drinkers: A 4-Year Follow-Up Study
Impacto
Scholar |
Otros documentos de la autoría: Jurado Barba, Rosa; Duque, Almudena; López-Trabada, José Ramón; Martínez Gras, Isabel; García-Gutiérrez, María Salud; Navarrete, Francisco; López-Muñoz, Francisco; Jiménez Arriero, Miguel Ángel; Avila, Cesar; Manzanares, Jorge; Rubio, Gabriel
Metadatos
Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/8033
comunitat-uji-handle3:10234/8636
comunitat-uji-handle4:
INVESTIGACIONEste recurso está restringido
http://dx.doi.org/10.1111/acer.13399 |
Metadatos
Título
The Modulation of the Startle Reflex as Predictor of Alcohol Use Disorders in a Sample of Heavy Drinkers: A 4-Year Follow-Up StudyAutoría
Fecha de publicación
2017Editor
WileyISSN
0145-6008; 1530-0277Cita bibliográfica
JURADO‐BARBA, Rosa, et al. The Modulation of the Startle Reflex as Predictor of Alcohol Use Disorders in a Sample of Heavy Drinkers: A 4‐Year Follow‐Up Study. Alcoholism: Clinical and Experimental Research, 2017, 41.6: 1212-1219.Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
http://onlinelibrary.wiley.com/doi/10.1111/acer.13399/fullVersión
info:eu-repo/semantics/publishedVersionPalabras clave / Materias
Resumen
Background
Previous studies demonstrated that patients with alcohol use disorders (AUDs) show altered startle reflex responses to alcohol-related stimuli. However, there is little information about the role of these ... [+]
Background
Previous studies demonstrated that patients with alcohol use disorders (AUDs) show altered startle reflex responses to alcohol-related stimuli. However, there is little information about the role of these altered responses in the development of AUDs. This study examined the startle reflex response to different visual stimuli and the role of these patterns in the development of AUDs in a 4-year follow-up.
Methods
Two hundred and thirty-nine (nondependent) heavy-drinking participants were selected. In the baseline period, the startle reflex responses to alcohol-related, aversive, appetitive, and neutral pictures were assessed. Startle reflex responses to these pictures were used as predictive variables. Status drinking (alcohol dependence and nondependence) assessed at 4-year follow-up was used as outcome measure.
Results
At the 4-year follow-up assessment, 46% of participants fulfilled DSM-IV alcohol abuse or dependence criteria. Alcohol dependence status was predicted by an attenuated startle reflex response to alcohol-related and aversive pictures.
Conclusions
This study revealed that an attenuated modulation of startle reflex response to alcohol-related and aversive stimuli could be used as a clinical marker to predict the development of AUDs in participants with previous alcohol consumption. [-]
Publicado en
Alcoholism: Clinical and Experimental Research, 2017, vol. 41, no 6Derechos de acceso
Copyright © John Wiley & Sons, Inc.
http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/restrictedAccess
http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/restrictedAccess
Aparece en las colecciones
- PSB_Articles [1294]