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An Internet-Based Intervention for Depression in Primary Care in Spain: A Randomiz ed Controlled Trial
dc.contributor.author | Montero-Marín, Jesús | |
dc.contributor.author | Araya, Ricardo | |
dc.contributor.author | Pérez Yus, Mari-Cruz | |
dc.contributor.author | Mayoral-Cleries, Fermin | |
dc.contributor.author | Gili, Margalida | |
dc.contributor.author | Botella, Cristina | |
dc.contributor.author | Baños, Rosa Maria | |
dc.contributor.author | Castro, Adoración | |
dc.contributor.author | Romero Sanchiz, Pablo | |
dc.contributor.author | López-del-Hoyo, Yolanda | |
dc.contributor.author | Nogueira-Arjona, Raquel | |
dc.contributor.author | Vives, Margalida | |
dc.contributor.author | Riera López del Amo, Antonio | |
dc.contributor.author | Garcia-Campayo, Javier | |
dc.date.accessioned | 2017-01-12T16:45:25Z | |
dc.date.available | 2017-01-12T16:45:25Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | MONTERO-MARÍN, Jesús, et al. An Internet-Based Intervention for Depression in Primary Care in Spain: A Randomized Controlled Trial. Journal of medical Internet research, 2016, vol. 18, núm. 8 8 | ca_CA |
dc.identifier.issn | 1439-4456 | |
dc.identifier.issn | 1438-8871 | |
dc.identifier.uri | http://hdl.handle.net/10234/165336 | |
dc.description.abstract | Background: Depression is the most prevalent cause of illness-induced disability worldwide. Face-to-face psychotherapeutic interventions for depression can be challenging, so there is a need for other alternatives that allow these interventions to be offered. One feasible alternative is Internet-based psychological interventions. This is the first randomized controlled trial (RCT) on the effectiveness of an Internet-based intervention on depression in primary health care in Spain. Objective: Our aim was to compare the effectiveness of a low-intensity therapist-guided (LITG) Internet-based program and a completely self-guided (CSG) Internet-based program with improved treatment as usual (iTAU) care for depression. Methods: Multicenter, three-arm, parallel, RCT design, carried out between November 2012 and January 2014, with a follow-up of 15 months. In total, 296 adults from primary care settings in four Spanish regions, with mild or moderate major depression, were randomized to LITG (n=96), CSG (n=98), or iTAU (n=102). Research completers at follow-up were 63.5%. The intervention was Smiling is Fun, an Internet program based on cognitive behavioral therapy. All patients received iTAU by their general practitioners. Moreover, LITG received Smiling is Fun and the possibility of psychotherapeutic support on request by email, whereas CSG received only Smiling is Fun. The main outcome was the Beck Depression Inventory-II at 3 months from baseline. Mixed-effects multilevel analysis for repeated measures were undertaken. Results: There was no benefit for either CSG [(B coefficient=-1.15; P=.444)] or LITG [(B=-0.71; P=.634)] compared to iTAU, at 3 months. There were differences at 6 months [iTAU vs CSG (B=-4.22; P=.007); iTAU vs LITG (B=-4.34; P=.005)] and 15 months [iTAU vs CSG (B=-5.10; P=.001); iTAU vs LITG (B=-4.62; P=.002)]. There were no differences between CSG and LITG at any time. Adjusted and intention-to-treat models confirmed these findings. Conclusions: An Internet-based intervention for depression combined with iTAU conferred a benefit over iTAU alone in the Spanish primary health care system. Trial Registration: Clinicaltrials.gov NCT01611818; https://register.clinicaltrials.gov/prs/app/action/SelectProtocol? selectaction=Edit&uid=U0001NPQ&ts=2&cx=gctdh2&sid=S0003KJ6 (Archived by WebCite at http://www.webcitation.org/6jbsUvUDz) | ca_CA |
dc.description.sponsorShip | This study was financed by the Instituto de Salud Carlos III of the Spanish Ministry of Economy and Competitiveness with the PI10/01083 grant (Eficacia y coste-efectividad de un programa de psicoterapia asistida por ordenador para el tratamiento de la depresión mayor en atención primaria: estudio controlado, randomizado y cualitativo). The project also received funding from the Network for Prevention and Health Promotion in primary Care (RD12/0005) grant from the Instituto de Salud Carlos III of the Ministry of Economy and Competitiveness (Spain), co-financed with European Union ERDF funds. | ca_CA |
dc.format.extent | 13 p. | ca_CA |
dc.format.mimetype | application/pdf | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | JMIR Publications | ca_CA |
dc.relation.isPartOf | Journal of medical Internet research, 2016, vol. 18, núm. 8 | ca_CA |
dc.rights | © Jesús Montero-Marín, Ricardo Araya, María C Pérez-Yus, Fermín Mayoral, Margalida Gili, Cristina Botella, Rosa Baños, Adoración Castro, Pablo Romero-Sanchiz, Yolanda López-Del-Hoyo, Raquel Nogueira-Arjona, Margarita Vives, Antoni Riera, Javier García-Campayo. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 26.08.2016. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included. | ca_CA |
dc.rights | Atribución-ShareAlike 4.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by-sa/4.0/ | * |
dc.subject | Depression | ca_CA |
dc.subject | Randomized Controlled Trial (RCT) | ca_CA |
dc.subject | Internet-based intervention | ca_CA |
dc.title | An Internet-Based Intervention for Depression in Primary Care in Spain: A Randomiz ed Controlled Trial | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | https://doi.org/10.2196/jmir.5695 | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | ca_CA |
dc.relation.publisherVersion | http://www.jmir.org/2016/8/e231/ | ca_CA |
dc.type.version | info:eu-repo/semantics/publishedVersion | ca_CA |
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Excepto si se señala otra cosa, la licencia del ítem se describe como: © Jesús Montero-Marín, Ricardo Araya, María C Pérez-Yus, Fermín Mayoral, Margalida Gili, Cristina Botella, Rosa Baños, Adoración Castro, Pablo Romero-Sanchiz, Yolanda López-Del-Hoyo, Raquel Nogueira-Arjona, Margarita Vives, Antoni Riera, Javier García-Campayo. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 26.08.2016.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.