• openAccess   Enzymatic Δ1-Dehydrogenation of 3-Ketosteroids—Reconciliation of Kinetic Isotope Effects with the Reaction Mechanism 

      Glanowski, Michał; Wójcik, Patrycja; Procner, Magdalena; Borowski, Tomasz; Lupa, Dawid; Mielczarek, Przemysław; Oszajca, Maria; Świderek, Katarzyna; Moliner, Vicent; Bojarski, Andrzej; Szaleniec, Maciej American Chemical Society (2021-07-02)
      Δ1-Dehydrogenation of 3-ketosteroids catalyzed by flavin adenine dinucleotide (FAD)-dependent 3-ketosteroid dehydrogenases (Δ1-KSTD) is a crucial step in steroid degradation and synthesis of several steroid drugs. The ...