Diamine acylation with amino acid derivatives: an example of proximity effect in organic reactivity induced by supramolecular aggregation

Thumbnail
Impact
Share
Show METS | MarcXML
Export to
Export to Mendeley
Metadata
Show full item record

comunitat-uji-handle:10234/9

comunitat-uji-handle2:10234/7053

comunitat-uji-handle3:10234/8639

INVESTIGACION

This resource is restricted

http://dx.doi.org/10.1016/j.tetlet.2015.01.094

Metadata

Title
Diamine acylation with amino acid derivatives: an example of proximity effect in organic reactivity induced by supramolecular aggregation
Author (s)
Felip-León, CarlesOrcidResearcherID;
Segarra Maset, María Dolores;
Escuder, BeatriuOrcidResearcherID;
Miravet, Juan F.
Date
2015-02
URI
http://hdl.handle.net/10234/156589
Publisher version
http://www.sciencedirect.com/science/article/pii/S0040403915001215
DOI
http://dx.doi.org/10.1016/j.tetlet.2015.01.094
Publisher
Elsevier
Abstract
Unexpected high yields of diamide 3 are obtained in the reaction of 1,3-propanediamine with an activated ester of l-valine (1) under adverse proportions of the reactants, namely in the presence of an excess of 1,3-p ... [+]
Unexpected high yields of diamide 3 are obtained in the reaction of 1,3-propanediamine with an activated ester of l-valine (1) under adverse proportions of the reactants, namely in the presence of an excess of 1,3-propanediamine. It is observed using different conditions that the yield of difunctionalized compound is considerably higher than that expected from a statistical distribution of products. Proximity effects associated to supramolecular interactions explain the described reactivity. [-]
Subject
Bibliographic citation
Felip-León, Carles, et al. "Diamine acylation with amino acid derivatives: an example of proximity effect in organic reactivity induced by supramolecular aggregation." Tetrahedron Letters 56.9 (2015): 1132-1134.
Type
info:eu-repo/semantics/article
Rights
Copyright © 2015 Elsevier Ltd. All rights reserved.
info:eu-repo/semantics/restrictedAccess
This item appears in the folowing collection(s)