Listar por tema "tubulin"
Mostrando ítems 1-3 de 3
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N-alpha-Aminoacyl Colchicines as Promising Anticancer Agents
Bentham Science Publishers (2020-12-29)Background: In the last years, many efforts have been made to find colchicine derivatives with reduced toxicity. Additionally, the deregulation of amino acid uptake by cancer cells provides an opportunity to improve ... -
Probing Tubulin-Blocked State of VDAC by Varying Membrane Surface Charge
Biophysical Society (2012-05) -
Synthesis of Combretastatin A-4 and 3 0 -Aminocombretastatin A-4 derivatives with Aminoacid Containing Pendants and Study of their Interaction with Tubulin and as Downregulators of the VEGF, hTERT and c-Myc Gene Expression
MDPI (2020)Natural product combretastatin A-4 (CA-4) and its nitrogenated analogue 3 0 -aminocombretastatin A-4 (AmCA-4) have shown promising antitumor activities. In this study, a range of CA-4 and AmCA-4 derivatives containing ...