Listar por tema "Macrolides"
Mostrando ítems 1-3 de 3
-
Stereoselective synthesis of a C1-C18 fragment of amphidinolides G and H
Elsevier (2013-04)A stereoselective synthesis of a C1–C18 segment of the structure of the cytotoxic macrolides amphidinolides G and H is reported. The target compound was retrosynthetically disconnected into three fragments. In the synthetic ... -
Stereoselective synthesis of the cytotoxic macrolide aspergillide B
Elsevier (2009)A total, stereoselective synthesis of the cytotoxic macrolide aspergillide B has been performed. A cross metathesis and a C-glycosidation via a Mukaiyama-type aldol reaction were key features of the synthesis. The macrocyclic ... -
Synthesis and biological properties of the cytotoxic 14-membered macrolides aspergillide A and B
Wiley (2010-11-09)Total, stereoselective syntheses of the naturally occurring, cytotoxic macrolides aspergillide A and B are described. Olefin metatheses and asymmetric allylations were key steps in the synthetic sequences. Cytotoxicity ...