• openAccess   Stereoselective synthesis of a C1-C18 fragment of amphidinolides G and H 

      García Fortanet, Jorge; Formentín, Pilar; Diaz-Oltra, Santiago; Murga, Juan; Carda, Miguel; Marco, J. Alberto Elsevier (2013-04)
      A stereoselective synthesis of a C1–C18 segment of the structure of the cytotoxic macrolides amphidinolides G and H is reported. The target compound was retrosynthetically disconnected into three fragments. In the synthetic ...
    • closedAccess   Stereoselective synthesis of the cytotoxic macrolide aspergillide B 

      Diaz-Oltra, Santiago; Angulo-Pachón, César A.; Kneeteman, María N.; Murga, Juan; Carda, Miguel; Marco, J. Alberto Elsevier (2009)
      A total, stereoselective synthesis of the cytotoxic macrolide aspergillide B has been performed. A cross metathesis and a C-glycosidation via a Mukaiyama-type aldol reaction were key features of the synthesis. The macrocyclic ...
    • closedAccess   Synthesis and biological properties of the cytotoxic 14-membered macrolides aspergillide A and B 

      Diaz-Oltra, Santiago; Angulo-Pachón, César A.; Murga, Juan; Falomir, Eva; Carda, Miguel; Marco, J. Alberto Wiley (2010-11-09)
      Total, stereoselective syntheses of the naturally occurring, cytotoxic macrolides aspergillide A and B are described. Olefin metatheses and asymmetric allylations were key steps in the synthetic sequences. Cytotoxicity ...