Listar por autoría "f47d8ce0-58d4-4756-a29d-ceca9004f7f7"
Mostrando ítems 1-20 de 42
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Análisis de la asociación entre sexo y diferencias en pigmentación humana según el genotipo del gen MC1R
Hernando, Barbara; Ibarrola-Villava, Maider; Llorca-Cardeñosa, Marta J.; Ribas, Gloria; Martinez-Cadenas, Conrado Universitat Jaume I (2016)Introducción: La pigmentación cutánea basal y la respuesta al sol por bronceamiento son rasgos hereditarios influidos por varios genes, entre los que el gen mc1r es uno de los más importantes. Mutaciones en este gen afectan ... -
Association between several immune response-related genes and the effectiveness of biological treatments in patients with moderate-to-severe psoriasis
Loras Monfort, Alba; Gil-Barrachina, Marta; Hernando, Barbara; Pérez-Pastor, Gemma María; Martinez-Domenech, Alvaro; Mahiques, Laura; PITARCH BORT, GERARD; Valcuende-Cavero, Francisca; Ballester, Rosa; Marques-Torrejon, Maria Angeles; Martinez-Cadenas, Conrado Wiley (2024-01-04)Biological therapies are safer and more effective against psoriasis than conventional treatments. Even so, 30–50% of psoriatic patients show an inadequate response, which is associated with individual genetic heterogeneity. ... -
Cardiac damage biomarkers and heart rate variability following a 118-km mountain race: relationship with performance and recovery
MARTINEZ-NAVARRO, IGNACIO; Sánchez-Gómez, Juan M.; Collado-Boira, Eladio; Hernando, Barbara; Panizo, Nayara Uludag University. Medical Faculty (2019-12)This study aimed to assess the release of cardiac damage biomarkers jointly with cardiac autonomic modulation after a mountain ultramarathon. Such knowledge and the possible relationship of these markers with race time is ... -
Effect of mountain ultramarathon distance competition on biochemical variables, respiratory and lower-limb fatigue
MARTINEZ-NAVARRO, IGNACIO; Sanchez-Gómez, Juan Miguel; Aparicio, Inma; Priego Quesada, Jose Ignacio; Pérez-Soriano, Pedro; Collado-Boira, Eladio; Hernando, Barbara; Hernando, Carlos Public Library of Science (2020)The study aimed at assessing the acute physiological effects of running a 65-km vs a 107- km mountain ultramarathon. Nineteen athletes (15 males and 4 females) from the shorter race and forty three athletes (26 males and ... -
Effects of wearing a full body compression garment during recovery from an ultra-trail race
MARTINEZ-NAVARRO, IGNACIO; Aparicio, Inma; Priego Quesada, Jose Ignacio; Pérez-Soriano, Pedro; Collado-Boira, Eladio; Hernando, Barbara; Hernando, Carlos Taylor & Francis (2020-06-30)In sport disciplines with high levels of muscle damage such as an ultra-trail competition, full body compression garments (FBCG) may have an ergogenic effect during the recovery process. The aim of the study was to assess ... -
Establishing cut-points for physical activity classification using triaxial accelerometer in middle-aged recreational marathoners
Hernando, Carlos; HERNANDO, CARLA; Collado-Boira, Eladio; Panizo, Nayara; MARTINEZ-NAVARRO, IGNACIO; Hernando, Barbara Plos (2018-08)The purpose of this study was to establish GENEA (Gravity Estimator of Normal Everyday Activity) cut-points for discriminating between six relative-intensity activity levels in middle-aged recreational marathoners. ... -
Estimation of energy consumed by middle-aged recreational marathoners during a marathon using accelerometry-based devices
Hernando, Carlos; HERNANDO, CARLA; MARTINEZ-NAVARRO, IGNACIO; Collado-Boira, Eladio; Panizo, Nayara; Hernando, Barbara Nature Research (2020)As long-distance races have substantially increased in popularity over the last few years, the improvement of training programs has become a matter of concern to runners, coaches and health professionals. triaxial ... -
Evolución de la masa corporal, la altura y el IMC en participantes del Ultratrail CSP-115
Chiva-Bartoll, Oscar; Hernando, Barbara; Martínez Navarro, I .; Collado-Boira, Eladio; Porcar, V .; Hernando, Carlos Asociación Didáctica Andalucia - Didactic Association Andalucía (2016)Introducción: este estudio analiza, en 32 participantes que finalizaron el Ultratrail - CSP - 115, los cambios antropométricos sufridos en cuanto a masa corporal, altura e índice de masa corporal ... -
Factores de riesgo asociados a padecer cáncer de piel de células basales y escamosas en el Mediterráneo
Gil-Barrachina, Marta; Hernando, Barbara; Martinez-Cadenas, Conrado Publicacions de la Universitat Jaume I. Servei de Comunicació i Publicacions (2020)Introducción: Los cánceres de células basales (BCC) y de células escamosas (SCC), clasificados como cánceres cutáneos no-melanoma, son los de mayor incidencia en todo el mundo. Los principales factores etiológicos ... -
‘Game of Clones’ Aplicación de la secuenciación masiva en el estudio de la evolución genómica del melanoma
Aguilar Rambla, Ana; Hernando, Barbara; Martinez-Cadenas, Conrado Publicacions de la Universitat Jaume I. Servei de Comunicació i Publicacions (2022)Introducción: Tener un mayor conocimiento del inicio de la carcinogénesis a nivel molecular es esencial para definir nuevos biomarcadores que mejoren el diagnóstico, tratamiento y pronóstico del paciente. Objetivos: ... -
Genetic 3’UTR variation is associated with human pigmentation characteristics and sensitivity to sunlight
Hernando, Barbara; Peña-Chilet, Maria; Ibarrola-Villava, Maider; Martín González, Manuel; Gómez Fernández, Cristina; Ribas, Gloria; Martinez-Cadenas, Conrado Wiley (2017-10)Sunlight exposure induces signalling pathways leading to the activation of melanin synthesis and tanning response. MicroRNAs (miRNAs) can regulate the expression of genes involved in pigmentation pathways by binding to the ... -
Genetic determinants of freckle occurrence in the Spanish population: Towards ephelides prediction from human DNA samples
Hernando, Barbara; Ibáñez Gual, Maria Victoria; Deserio Cuesta, Julio Alberto; Soria Navarro, Raquel; Vilar Sastre, Inca; Martinez-Cadenas, Conrado Elsevier (2018-03)Prediction of human pigmentation traits, one of the most differentiable externally visible characteristics among individuals, from biological samples represents a useful tool in the field of forensic DNA phenotyping. ... -
Genetic variants associated with skin photosensitivity in a southern European population from Spain
Hernando, Barbara; Sanz-Page, Elena; PITARCH BORT, GERARD; Mahiques, Laura; Valcuende-Cavero, Francisca; Martinez-Cadenas, Conrado Wiley (2018)Background/Purpose: Recent GWAS studies, mostly performed in populations of North European origin, have identified the genetic loci associated with pigmentation, sun sensitivity, freckling and skin cancer ... -
La genètica de la pigmentació humana i de la predisposició al càncer de pell
Hernando, Barbara; Martinez-Cadenas, Conrado Agrupació Borrianenca de Cultura (2016)Els trets de pigmentació humana, incloent-hi el color dels ulls, de la pell i del cabell, són els trets físics més visibles i diferenciables entre individus. La variació en la pigmentació entre individus està influenciada ... -
Hydration status, executive function and response to orthostatism following a 118-km race: are they interrelated?
Martínez Navarro, I .; Chiva-Bartoll, Oscar; Hernando, Barbara; Collado-Boira, Eladio; Porcar Blanch, Vicente; Hernando, Carlos National Strength and Conditioning Association (2018-02)The present study aimed to explore whether blood pressure (BP) and heart rate (HR) variability (HRV) responsiveness to orthostatism, jointly with executive function (EF) performance, was diminished after an ultra-endurance ... -
Identificación de las variantes genéticas asociadas al color de ojos verde y a la presencia de anillo peripupilar en humanos
Suárez-Collado, Ángela; Hernando, Barbara; Martinez-Cadenas, Conrado Publicacions de la Universitat Jaume I. Servei de Comunicació i Publicacions (2019)Introducción: El color de los ojos, rasgo hereditario poligénico, es una de las características físicas más visibles y diferenciables entre humanos. Por ello, la predicción del color del iris es ampliamente utilizada en ... -
Identificación de variantes genéticas asociadas a la sensibilidad solar
Deserio Cuesta, Julio Alberto; Soria Navarro, Raquel; Vilar Sastre, Inca; Hernando, Barbara; Martinez-Cadenas, Conrado Publicacions de la Universitat Jaume I. Servei de Comunicació i Publicacions (2018)Introducción: La sensibilidad a la radiación ultravioleta está determinada por característicaspigmentarias influenciadas por varios genes. Ciertos rasgos de la pigmentación,como tener un color de piel claro, tener muchas ... -
Immediate and 24-h post-marathon cardiac troponin T is associated with relative exercise intensity
MARTINEZ-NAVARRO, IGNACIO; Sánchez-Gómez, Juan M.; Sanmiguel, D.; Collado-Boira, Eladio; Hernando, Barbara; Panizo, Nayara; Hernando, Carlos Springer (2020-05-28)Purpose We aimed at exploring whether cardiopulmonary ftness, echocardiographic measures and relative exercise intensity were associated with high-sensitivity cardiac troponin T (hs-TNT) rise and normalization following ... -
Impact of Plasma Oxidative Stress Markers on Post-race Recovery in Ultramarathon Runners: A Sex and Age Perspective Overview
Guerrero, Carlos; Collado-Boira, Eladio; MARTINEZ-NAVARRO, IGNACIO; Hernando, Barbara; Hernando, Carlos; Baliño, Pablo; Muriach, Maria MDPI (2021-03)Oxidative stress has been widely studied in association to ultra-endurance sports. Although it is clearly demonstrated the increase in reactive oxygen species and free radicals after these extreme endurance exercises, the ... -
In vitro behavior and UV response of melanocytes derived from carriers of CDKN2A mutations and MC1R variants
Hernando, Barbara; Swope, Vike B.; Guard, Steven; Starner, Renny J.; Choi, Kevin; Anwar, Ayesha; Cassidy, Pamela; Leachman, Sancy; Kadekaro, Ana Luisa; Bennett, Dorothy; Abdel-Malek, Zalfa Wiley (2019)Coinheritance of germline mutation in cyclin-dependent kinase inhibitor 2A (CDKN2A) and loss- of- function (LOF) melanocortin 1 receptor (MC1R) variants is clinically associ-ated with exaggerated risk for melanoma. To ...