Listar por autoría "edc63fdc-c6f8-44d0-96a3-0a387fb11924"

Mostrando ítems 1-4 de 4

    • openAccess   Association of TYR SNP rs1042602 with Melanoma Risk and Prognosis 

      Sevilla Mambrilla, Arrate; Sánchez-Diez, Ana; Cobo Sustacha, Sofía; Izagirre Arribalzaga, Neskuts; Martinez-Cadenas, Conrado; Marti, Rosa M; Puértolas, Teresa; De Unamuno Bustos, Blanca; Bañuls, José; Izu, Rosa; Gardeazabal, Jesús; Asumendi, Aintzane; Boyano, María D.; Alonso, Santos MDPI (2023)
      Cutaneous melanoma is the most aggressive of skin tumors. In order to discover new biomarkers that could help us improve prognostic prediction in melanoma patients, we have searched for germline DNA variants associated ...

    • openAccess   Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma 

      Santos, Alonso; Ribas, Gloria; Ibarrola-Villava, Maider; Peña Chilet, María; Martinez-Cadenas, Conrado; Gardeazabal, Jesús; Careaga, Jesús María; Pérez-Yarza, Gorka; Sánchez-Díez, Ana; Ratón-Nieto, Juan Antonio; Arroyo-Berdgo, Yoana; Carretero, Gregorio; Martín González, Manuel; Gómez Fernández, Cristina; Nagore, Eduardo; Asumendi, Aintzane; Boyano, Dolores Public Library of Science (2014)
      Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic ...

    • openAccess   Simultaneous purifying selection on the ancestral MC1R allele and positive selection on the melanoma-risk allele V60L in South Europeans 

      Martinez-Cadenas, Conrado; López, Saioa; Ribas, Gloria; Flores, Carlos; García, Oscar; Sevilla, Arrate; Smith-Zubiaga, I.; Ibarrola-Villava, Maider; Pino-Yanes, M .; Gardeazabal, Jesús; Boyano, Dolores; García de Galdeano, Alicia; Izagirre, Neskuts; de la Rúa, Concepción; Alonso, Santos Oxford University Press (2013)
      In humans, the geographical apportionment of the coding diversity of the pigmentary locus melanocortin-1 receptor (MC1R) is, unusually, higher in Eurasians than in Africans. This atypical observation has been interpreted ...

    • openAccess   The Interplay between Natural Selection and Susceptibility to Melanoma on Allele 374F of SLC45A2 Gene in a South European Population 

      López, Saioa; García, Oscar; Yurrebaso, Iñaki; Flores, Carlos; Acosta-Herrera, Marialbert; Chen, Hua; Gardeazabal, Jesús; Careaga, Jesús María; Boyano, Dolores; Sánchez, Ana; Ratón-Nieto, Juan Antonio; Sevilla, Arrate; Smith-Zubiaga, I.; García de Galdeano, Alicia; Martinez-Cadenas, Conrado; Izagirre, Neskuts; de la Rúa, Concepción; Alonso, Santos Public Library of Science (2014)
      We aimed to study the selective pressures interacting on SLC45A2 to investigate the interplay between selection and susceptibility to disease. Thus, we enrolled 500 volunteers from a geographically limited population ...