Listar por autoría "d25caa08-244b-48f0-b867-28e86f089f14"

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    • closedAccess   Effects of pharmacological agents, sleep deprivation, hypoxia and transcranial magnetic stimulation on electroencephalographic rhythms in rodents: Towards translational challenge models for drug discovery in Alzheimer’s disease 

      Babiloni, Claudio; Infarinato, Francesco; Aujard, Fabienne; Bastlund, Jesper Frank; Bentivoglio, Marina; Bertini, Giuseppe; Del Percio, Claudio; Fabene, Paolo Francesco; Forloni, GianLuigi; Herrero Ezquerro, María Trinidad; Noè, Francesco Mattia; Pifferi, Fabien; Ros Bernal, Francisco; Christensen, Ditte Zerlang; Dix, Sophie; Richardson, Jill C.; Lamberty, Yves; Drinkenburg, Wilhelmus; Rossini, Paolo Maria Elsevier (2013)
      Different kinds of challenge can alter spontaneous ongoing electroencephalographic (EEG) rhythms in animal models, thus providing paradigms to evaluate treatment effects in drug discovery. The effects of challenges represented ...

    • closedAccess   Evaluation of symptomatic drug effects in Alzheimer’s disease: strategies for prediction of efficacy in humans 

      Deguil, J.; Ravasi, L.; Auffret, A.; Babiloni, Claudio; Bartrés Faz, David; Bragulat, V.; Cassé-Perro, C.; Colavito, V.; Herrero Ezquerro, María Trinidad; Lamberty, Yves; Lanteaume, L.; Pemberton, D.; Pifferi, Fabien; Richardson, Jill C.; Schenker, Esther; Blin, Olivier; Tarragon Cros, Ernesto; Bordet, Regis Elsevier (2013)
      In chronic diseases such as Alzheimer's disease (AD), the arsenal of biomarkers available to determine the effectiveness of symptomatic treatment is very limited. Interpretation of the results provided in literature is ...

    • closedAccess   Memantine prevents reference and working memory impairment caused by sleep deprivation in both young and aged Octodon degus 

      Herrero Ezquerro, María Trinidad; Tarragon Cros, Ernesto; López, Dolores; Estrada, Cristina; González Cuello, Ana; Ros Gómez, Carmen María; Lamberty, Yves; Pifferi, Fabien; Cella, Massimo; Canovi, Mara; Guiso, Giovanna; Gobbi, Marco; Fernández Villalba, Emiliano; Blin, Olivier; Bordet, Regis; Richardson, Jill C. Elsevier (2014-10)
      Memory loss is one of the key features of cognitive impairment in either aging, Mild Cognitive Impairment (MCI) or dementia. Pharmacological treatments for memory loss are today focused on addressing symptomatology. One ...

    • openAccess   Octodon degus: A Model for the Cognitive Impairment Associated with Alzheimer's Disease 

      Tarragon Cros, Ernesto; López, Dolores; Estrada, Cristina; Schenker, Esther; Bordet, Regis; Richardson, Jill C.; Herrero Ezquerro, María Trinidad; González Cuello, Ana Wiley (2013-05-27)
      Octodon degus (O. degus) is a diurnal rodent that spontaneously develops several physiopathological conditions, analogous in many cases to those experienced by humans. In light of this, O. degus has recently been identified ...