Listar por autoría "d0abb71b-a05c-42f4-b34d-826da4c4fc65"
Mostrando ítems 1-1 de 1
-
Deimmunization for gene therapy: host matching of synthetic zinc finger constructs enables long-term mutant Huntingtin repression in mice
Agustín-Pavón, Carmen; Mielcarek, Michal; Garriga-Canut, Mireia; Isalan, Mark BioMed Central (2016)Background: Synthetic zinc finger (ZF) proteins can be targeted to desired DNA sequences and are useful tools for gene therapy. We recently developed a ZF transcription repressor (ZF-KOX1) able to bind to expanded DNA ...