Listar por autoría "9dcb63c6-938e-46f6-8f54-f0696eb7313b"

Mostrando ítems 1-9 de 9

    • openAccess   Furanchalcone–biphenyl hybrids: synthesis, in silico studies, antitrypanosomal and cytotoxic activities 

      García, Elisa; Ochoa, Rodrigo; Vasquez, Isabel; Conesa Milián, Laura; Carda, Miguel; Yepes, Andrés; Vélez, Iván D.; Robledo, Sara M.; Cardona Galeano, Wilson Isidro Springer Verlag (2019)
      The synthesis, antitrypanosomal, and cytotoxic activities of 17 furanchalcone derivatives are described herein. The structure of the synthesized products was elucidated by a combination of spectrometric analyses. The ...

    • openAccess   Synthesis and Antiproliferative Activity of 3 and 7-Styrylcoumarins 

      Herrera-R, Angie; Castrillón, Wilson; Otero, Elver; Ruiz, Esneyder; Carda, Miguel; Agut, Raúl; Naranjo Preciado, Tonny; Moreno, Gustavo; Maldonado, María Elena; Cardona Galeano, Wilson Isidro Springer Verlag (2018)
      A series of styrylcoumarins were obtained via Mizoroki-Heck reactions between 3-bromo-4-methyl7-(octyloxy)-2H-chromen-2-one or 2-oxo-2H-chromen-7-yl trifluoromethanesulfonate and functionalized styrenes. The structures ...

    • closedAccess   Synthesis and antiprotozoal activity of furanchalcone–quinoline, furanchalcone–chromone and furanchalcone–imidazole hybrids 

      García, Elisa; Coa, Juan Carlos; Otero, Elver; Carda, Miguel; Vélez, Iván D.; Robledo, Sara M.; Cardona Galeano, Wilson Isidro Springer Verlag (2018)
      We report herein the synthesis and biological activities (cytotoxicity, leishmanicidal, and trypanocidal) of several furanchalcone–quinoline, furanchalcone–chromone, and furanchalcone–imidazole hybrids. The synthesized ...

    • openAccess   Synthesis and in-vitro evaluation of s-allyl cysteine ester-caffeic acid amide hybrids as potential anticancer agents 

      Castrillón, Wilson; Herrera-R, Angie; Prieto, Laura Juliana; Conesa Milián, Laura; Carda, Miguel; Naranjo Preciado, Tonny; Maldonado, María Elena; Cardona Galeano, Wilson Isidro Shahid Beheshti University of Medical Sciences, School of Pharmacy (2019)
      We have synthesized a series of S-allyl cysteine ester-caffeic acid amide hybrids and evaluated them in order to determine their possible anticancer activity and selectivity in colorectal cancer, which is still one of the ...

    • openAccess   Synthesis and leishmanicidal activity of cinnamic acid esters: structure–activity relationship 

      Otero, Elver; Robledo, Sara M.; Diaz-Oltra, Santiago; Carda, Miguel; Muñoz, Diana; Paños Pérez, Julián; Vélez, Iván D.; Cardona Galeano, Wilson Isidro Springer (2014)
      Several cinnamic acid esters were obtained via Fischer esterification of cinnamic acids derivatives with aliphatic alcohols. Structures of the products were elucidated by spectroscopic analysis. The synthesized compounds ...

    • openAccess   Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids 

      Coa, Juan Carlos; Yepes, Andrés; Carda, Miguel; Conesa Milián, Laura; Upegui Zapata, Yulieth Alexandra; Robledo, Sara M.; Cardona Galeano, Wilson Isidro Wiley (2020-03-13)
      The synthesis, in silico studies, antiprotozoal and cytotoxic activities of eleven quinoline‐biphenyl hybrids are described herein. The structure of the synthesized products was elucidated by a combination of spectrometric ...

    • openAccess   Synthesis, Leishmanicidal and Cytotoxic Activity of Triclosan-Chalcone, Triclosan-Chromone and Triclosan-Coumarin Hybrids 

      Otero, Elver; Vergara, Sebastián; Robledo, Sara M.; Cardona Galeano, Wilson Isidro; Carda, Miguel; Vélez, Iván D.; Rojas, Carlos; Otálvaro, Felipe (MDPI) Digital Publishing Institute (2014)
      Twelve hybrids derived from triclosan were obtained via Williamson etherification of O-triclosan alkyl bromide plus chalcone and O-coumarin or O-chromone alkyl bromide plus triclosan, respectively. Structures of the products ...

    • closedAccess   Synthesis, leishmanicidal, trypanocidal and cytotoxic activity of quinoline-hydrazone hybrids 

      Coa, Juan Carlos; Castrillón, Wilson; Cardona Galeano, Wilson Isidro; Carda, Miguel; Ospina, Victoria; Muñoz, July Andrea; Vélez, Iván D.; Robledo, Sara M. Elsevier (2015)
      Cutaneous leishmaniasis and Chagas disease are vector-borne parasitic disease causing serious risks to million people living in poverty-stricken areas. Both diseases are a major health problem in Latin America, and currently ...

    • openAccess   Triclosan-caffeic acid hybrids: Synthesis, leishmanicidal, trypanocidal and cytotoxic activities 

      Otero, Elver; García, Elisa; Palacios, Génesis; Yepes, Lina M.; Carda, Miguel; Agut, Raúl; Vélez, Iván D.; Cardona Galeano, Wilson Isidro; Robledo, Sara M. Elsevier (2017-09-29)
      The synthesis, cytotoxicity, anti-leishmanial and anti-trypanosomal activities of twelve triclosan-caffeic acid hybrids are described herein. The structure of the synthesized products was elucidated by a com- bination ...