• openAccess   Comparison of pharmaceutical, illicit drug, alcohol, nicotine and caffeine levels in wastewater with sale, seizure and consumption data for 8 European cities 

      Baz Lomba, Jose Antonio; Salvatore, Stefania; GRACIA LOR, EMMA; Bade, Richard; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Reid, Malcolm; Rousis, Nikolaos I; Ryu, Yeonsuk; de Voogt, Pim; Bramness, Jorgen; Thomas, Kevin V. BioMed Central (2016)
      Background: Monitoring the scale of pharmaceuticals, illicit and licit drugs consumption is important to assess the needs of law enforcement and public health, and provides more information about the different trends within ...
    • closedAccess   Comparison of phosphodiesterase type V inhibitors use in eight European cities through analysis of urban wastewater 

      Causanilles, Ana; Rojas Cantillano, Daniela; Emke, Erik; Bade, Richard; Baz Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; GRACIA LOR, EMMA; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann Kathrin; van Nuijs, Alexander; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin; de Voogt, Pim Elsevier (2018-06)
      In this work a step forward in investigating the use of prescription drugs, namely erectile dysfunction products, at European level was taken by applying the wastewater-based epidemiology approach. 24-h composite samples ...
    • closedAccess   Enantiomeric profiling of quinolones and quinolones resistance gene qnrS in European wastewaters 

      Castrignano', Erika; Yang, Zhugen; Feil, Edward; Bade, Richard; Castiglioni, Sara; Causanilles, Ana; GRACIA LOR, EMMA; Hernandez, Felix; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin; de Voogt, Pim; Zuccato, Ettore; Kasprzyk-Hordern, Barbara Elsevier (2020)
      Wastewater-based epidemiology (WBE) was applied for the first time in seven cities across Europe with the aim of estimating quinolones consumption via the analysis of human urinary metabolites in wastewater. This report ...
    • closedAccess   Enantiomeric profiling of chiral illicit drugs in a pan-European study 

      Castrignanò, Erika; Yang, Zhugen; Bade, Richard; Baz Lomba, Jose Antonio; Castiglioni, Sara; Causanilles, Ana; Covaci, Adrian; GRACIA LOR, EMMA; Hernandez, Felix; Kinyua, Juliet; McCall, Ann Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Kasprzyk-Hordern, Barbara Elsevier (2018)
      The aim of this paper is to present the first study on spatial and temporal variation in the enantiomeric profile of chiral drugs in eight European cities. Wastewater-based epidemiology (WBE) and enantioselective analysis ...
    • openAccess   Estimation of caffeine intake from analysis of caffeine metabolites in wastewater 

      GRACIA LOR, EMMA; Rousis, Nikolaos I; Zuccato, Ettore; Bade, Richard; Baz Lomba, Jose Antonio; Castrignanò, Erika; Causanilles, Ana; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Plosz, Benedek; Ramin, Pedram; Ryu, Yeonsuk; Santos, Miguel M.; Thomas, Kevin V.; de Voogt, Pim; Yang, Zhugen; Castiglioni, Sara Elsevier (2017-12)
      Caffeine metabolites in wastewater were investigated as potential biomarkers for assessing caffeine intake in a population. The main human urinary metabolites of caffeine were measured in the urban wastewater of ten European ...
    • openAccess   Increased levels of the oxidative stress biomarker 8-iso-prostaglandin F2α in wastewater associated with tobacco use 

      Ryu, Yeonsuk; GRACIA LOR, EMMA; Bade, Richard; Baz Lomba, Jose Antonio; Bramness, Jorgen; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; Covaci, Adrian; de Voogt, Pim; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Reid, Malcolm; Thomas, Kevin V. Nature Publishing Group (2016)
      Wastewater analysis has been demonstrated to be a complementary approach for assessing the overall patterns of drug use by a population while the full potential of wastewater-based epidemiology has yet to be explored. ...
    • openAccess   Liquid chromatography-tandem mass spectrometry determination of synthetic cathinones and phenethylamines in influent wastewater of eight European cities 

      Bade, Richard; Bijlsma, Lubertus; Sancho, Juan V; Baz Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; GRACIA LOR, EMMA; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Hernandez, Felix Elsevier (2017)
      The popularity of new psychoactive substances (NPS) has grown in recent years, with certain NPS commonly and preferentially consumed even following the introduction of preventative legislation. With the objective to improve ...
    • openAccess   Liquid chromatography-tandem mass spectrometry determination of synthetic cathinones and phenethylamines in influent wastewater of eight European cities 

      Bade, Richard; Bijlsma, Lubertus; Sancho, Juan V; Baz Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; GRACIA LOR, EMMA; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Hernandez, Felix Elsevier (2017-02)
      The popularity of new psychoactive substances (NPS) has grown in recent years, with certain NPS commonly and preferentially consumed even following the introduction of preventative legislation. With the objective to improve ...
    • openAccess   Measuring biomarkers in wastewater as a new source of epidemiological information: current state and future perspectives 

      GRACIA LOR, EMMA; Castiglioni, Sara; Bade, Richard; Been, Frederic; Castrignanò, Erika; Covaci, Adrian; González-Mariño, Iria; Hapeshi, Evroula; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; Lai, Foon Yin; Letzel, Thomas; Lopardo, Luigi; Meyer, Markus R.; O'Brien, Jake; Ramin, Pedram; Rousis, Nikolaos I; Rydevik, Axel; Ryu, Yeonsuk; Santos, Miguel M.; Senta, Ivan; Thomaidis, Nikolaos; Veloutsou, Sofia; Yang, Zhugen; Zuccato, Ettore; Bijlsma, Lubertus Elsevier (2017-02)
      The information obtained from the chemical analysis of specific human excretion products (biomarkers) in urban wastewater can be used to estimate the exposure or consumption of the population under investigation to a defined ...
    • openAccess   Monitoring a large number of pesticides and transformation products in water samples from Spain and Italy 

      Rousis, Nikolaos I; Bade, Richard; Bijlsma, Lubertus; Zuccato, Ettore; Sancho, Juan V; Hernandez, Felix; Castiglioni, Sara Elsevier (2017-07)
      Assessing the presence of pesticides in environmental waters is particularly challenging because of the huge number of substances used which may end up in the environment. Furthermore, the occurrence of pesticide transformation ...
    • openAccess   Screening of Pharmaceuticals and Illicit Drugs in Wastewater and Surface Waters of Spain and Italy by High Resolution Mass Spectrometry using UHPLC-QTOF MS and LC-LTQ-Orbitrap MS 

      Bade, Richard; Rousis, Nikolaos I; Bijlsma, Lubertus; GRACIA LOR, EMMA; Castiglioni, Sara; Sancho, Juan V; Hernandez, Felix Springer (2015)
      The existence of pharmaceuticals and illicit drugs (PIDs) in environmental waters has led many analytical chemists to develop screening methods for monitoring purposes. Water samples can contain a huge number of possible ...
    • openAccess   Three years of wastewater surveillance for new psychoactive substances from 16 countries 

      Bade, Richard; Rousis, Nikolaos I; Adhikari, Sangeet; Baduel, Christine; Bijlsma, Lubertus; Bizani, Erasmia; Boogaerts, Tim; Burgard, Daniel A.; Castiglioni, Sara; Chappell, Andrew; Covaci, Adrian; Driver, Erin M.; Fabriz Sodré, Fernando; Fatta-Kassinos, Despo; Galani, Aikaterini; Gerber, Cobus; GRACIA LOR, EMMA; Gracia-Marín, Elisa; Halden, Rolf; Heath, Ester; Hernandez, Felix; Yin Lai, Foon; Lee, Heon-Jun; Laimou-Geraniou, Maria; Oh, Jeong-Eun; Olafsdottir, Kristin; Phung, Kaitlyn; Pineda Castro, Marco; Psichoudaki, Magda; Shao, Xueting; Salgueiro-González, Noelia; Silva Feitosa, Rafael; Silvino Gomes, Cezar; Subedi, Bikram; Löve, Arndís; Thomaidis, Nikolaos; Tran, Diana; van Nuijs, Alexander; Verovšek, Taja; Wang, Degao; White, Jason; Yargeau, Viviane; Zuccato, Ettore; Mueller, Jochen Elsevier (2023-05)
      The proliferation of new psychoactive substances (NPS) over recent years has made their surveillance complex. The analysis of raw municipal influent wastewater can allow a broader insight into community consumption patterns ...
    • closedAccess   Wastewater-Based Epidemiology as a Novel Biomonitoring Tool to Evaluate Human Exposure To Pollutants 

      GRACIA LOR, EMMA; Rousis, Nikolaos I; Hernandez, Felix; Zuccato, Ettore; Castiglioni, Sara ACS (2018-08-27)
      Humans are continuously exposed to pollutants by different routes, and human biomonitoring (HBM) is the tool commonly used to assess exposure to chemicals by measuring parent substances or metabolites in human specimens. ...
    • closedAccess   Wastewater-based epidemiology as a novel tool to evaluate human exposure to pesticides: Triazines and organophosphates as case studies 

      Rousis, Nikolaos I; GRACIA LOR, EMMA; Hernandez, Felix; Poretti, Francesco; Santos, Miguel M.; Zuccato, Ettore; Castiglioni, Sara Elsevier ScienceDirect (2021-06-22)
      Production and application of pesticides have risen remarkably in the last few decades. Even if they provide many benefits, they can be hazardous for humans and ecosystems when they are not used cautiously. Human exposure ...
    • closedAccess   Wastewater-based epidemiology to assess pan-European pesticide exposure 

      Rousis, Nikolaos I; GRACIA LOR, EMMA; Zuccato, Ettore; Bade, Richard; Baz Lomba, Jose Antonio; Castrignanò, Erika; Causanilles, Ana; Covaci, Adrian; de Voogt, Pim; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; Plosz, Benedek; Ramin, Pedram; Ryu, Yeonsuk; Thomas, Kevin; van Nuijs, Alexander; Yang, Zhugen; Castiglioni, Sara Elsevier (2017)
      Human biomonitoring, i.e. the determination of chemicals and/or their metabolites in human specimens, is the most common and potent tool for assessing human exposure to pesticides, but it suffers from limitations such as ...
    • openAccess   Workflow to facilitate the detection of new psychoactive substances and drugs of abuse in influent urban wastewater 

      Bade, Richard; van Herwerden, Denice; Rousis, Nikolaos I; Adhikari, Sangeet; Allen, Darren; Baduel, Christine; Bijlsma, Lubertus; Boogaerts, Tim; Burgard, Dan; Chappell, Andrew; Driver, Erin M.; Fabriz Sodré, Fernando; Fatta-Kassinos, Despo; GRACIA LOR, EMMA; Gracia-Marín, Elisa; Halden, Rolf; Heath, Ester; Keller, Emma; Krotulski, Alex; Lai, Foon Yin; Mueller, Jochen Elsevier (2024-03-08)
      The complexity around the dynamic markets for new psychoactive substances (NPS) forces researchers to develop and apply innovative analytical strategies to detect and identify them in influent urban wastewater. In this ...