Listar por autoría "4a71144c-69b2-4ec2-a0e8-927b49f4aa40"
Mostrando ítems 1-20 de 27
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3-Fluorophenmetrazine, a fluorinated analogue of phenmetrazine:Studies on in vivo metabolism in rat and human, in vitro metabolism in human CYP isoenzymes and microbial biotransformation in Pseudomonas Putida and wastewater using GC and LC coupled to(HR)-MS techniques
Mardal, Marie; Miserez, Bram; Bade, Richard; Portoles, Tania; Bischoff, Markus; Hernandez, Felix; Meyer, Markus R. Elsevier (2016-09)Wastewater-based epidemiology (WBE) as means to estimate illicit drug and new psychoactive substance (NPS) consumption with spatial and temporal resolution is gaining increasing attention. In order to evaluate a given NPS ... -
Comparison of pharmaceutical, illicit drug, alcohol, nicotine and caffeine levels in wastewater with sale, seizure and consumption data for 8 European cities
Baz Lomba, Jose Antonio; Salvatore, Stefania; GRACIA LOR, EMMA; Bade, Richard; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Reid, Malcolm; Rousis, Nikolaos I; Ryu, Yeonsuk; de Voogt, Pim; Bramness, Jorgen; Thomas, Kevin V. BioMed Central (2016)Background: Monitoring the scale of pharmaceuticals, illicit and licit drugs consumption is important to assess the needs of law enforcement and public health, and provides more information about the different trends within ... -
Comparison of phosphodiesterase type V inhibitors use in eight European cities through analysis of urban wastewater
Causanilles, Ana; Rojas Cantillano, Daniela; Emke, Erik; Bade, Richard; Baz Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; GRACIA LOR, EMMA; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann Kathrin; van Nuijs, Alexander; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin; de Voogt, Pim Elsevier (2018-06)In this work a step forward in investigating the use of prescription drugs, namely erectile dysfunction products, at European level was taken by applying the wastewater-based epidemiology approach. 24-h composite samples ... -
Critical evaluation of a simple retention time predictor based on LogKow as a complementary tool in the identification of emerging contaminants in water
Bade, Richard; Bijlsma, Lubertus; Sancho, Juan V; Hernandez, Felix Elsevier (2015)There has been great interest in environmental analytical chemistry in developing screening methods based on liquid chromatography–high resolution mass spectrometry (LC–HRMS) for emerging contaminants. Using HRMS, compound ... -
Critical review on the stability of illicit drugs in sewers and wastewater samples
McCall, Ann-Kathrin; Bade, Richard; Kinyua, Juliet; Lai, Foon Yin; Thai, Phong K.; Covaci, Adrian; Bijlsma, Lubertus; van Nuijs, Alexander; Ort, Christoph Elsevier (2015-10)Wastewater-based epidemiology (WBE) applies advanced analytical methods to quantify drug residues in wastewater with the aim to estimate illicit drug use at the population level. Transformation processes during transport ... -
Enantiomeric profiling of quinolones and quinolones resistance gene qnrS in European wastewaters
Castrignano', Erika; Yang, Zhugen; Feil, Edward; Bade, Richard; Castiglioni, Sara; Causanilles, Ana; GRACIA LOR, EMMA; Hernandez, Felix; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin; de Voogt, Pim; Zuccato, Ettore; Kasprzyk-Hordern, Barbara Elsevier (2020)Wastewater-based epidemiology (WBE) was applied for the first time in seven cities across Europe with the aim of estimating quinolones consumption via the analysis of human urinary metabolites in wastewater. This report ... -
Enantiomeric profiling of chiral illicit drugs in a pan-European study
Castrignanò, Erika; Yang, Zhugen; Bade, Richard; Baz Lomba, Jose Antonio; Castiglioni, Sara; Causanilles, Ana; Covaci, Adrian; GRACIA LOR, EMMA; Hernandez, Felix; Kinyua, Juliet; McCall, Ann Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Kasprzyk-Hordern, Barbara Elsevier (2018)The aim of this paper is to present the first study on spatial and temporal variation in the enantiomeric profile of chiral drugs in eight European cities. Wastewater-based epidemiology (WBE) and enantioselective analysis ... -
Estimation of caffeine intake from analysis of caffeine metabolites in wastewater
GRACIA LOR, EMMA; Rousis, Nikolaos I; Zuccato, Ettore; Bade, Richard; Baz Lomba, Jose Antonio; Castrignanò, Erika; Causanilles, Ana; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Plosz, Benedek; Ramin, Pedram; Ryu, Yeonsuk; Santos, Miguel M.; Thomas, Kevin V.; de Voogt, Pim; Yang, Zhugen; Castiglioni, Sara Elsevier (2017-12)Caffeine metabolites in wastewater were investigated as potential biomarkers for assessing caffeine intake in a population. The main human urinary metabolites of caffeine were measured in the urban wastewater of ten European ... -
Facilitating high resolution mass spectrometry data processing for screening of environmental water samples: An evaluation of two deconvolution tools
Bade, Richard; Causanilles, Ana; Emke, Erik; Bijlsma, Lubertus; Sancho, Juan V; Hernandez, Felix; de Voogt, Pim Elsevier (2016)A screening approach was applied to influent and effluent wastewater samples. After injection in a LC-LTQ-Orbitrap, data analysis was performed using two deconvolution tools, MsXelerator (modules MPeaks and MS Compare) and ... -
Increased levels of the oxidative stress biomarker 8-iso-prostaglandin F2α in wastewater associated with tobacco use
Ryu, Yeonsuk; GRACIA LOR, EMMA; Bade, Richard; Baz Lomba, Jose Antonio; Bramness, Jorgen; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; Covaci, Adrian; de Voogt, Pim; Hernandez, Felix; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Reid, Malcolm; Thomas, Kevin V. Nature Publishing Group (2016)Wastewater analysis has been demonstrated to be a complementary approach for assessing the overall patterns of drug use by a population while the full potential of wastewater-based epidemiology has yet to be explored. ... -
International snapshot of new psychoactive substance use: Case study of eight countries over the 2019/2020 new year period
Bade, Richard; White, Jason M.; Chen, Jingjing; Baz Lomba, Jose Antonio; Been, Frederic; Bijlsma, Lubertus; Universitat Jaume I. Departament de Química Física i Analítica; Burgard, Daniel A.; Castiglioni, Sara; Salgueiro-González, Noelia; Celma, Alberto; Universitat Jaume I. Departament de Química Física i Analítica; Chappell, Andrew; Emke, Erik; Steenbeek, Ruud; Wang, Degao; Zuccato, Ettore; Gerber, Cobus Elsevier (2021-02-03)There is considerable concern around the use of new psychoactive substances (NPS), but still little is known about how much they are really consumed. Analysis by forensics laboratories of seized drugs and post-mortem samples ... -
Investigating the appearance of new psychoactive substances in South Australia using wastewater and forensic data.
Bade, Richard; Stockham, Peter; Painter, Ben; Celma, Alberto; Bijlsma, Lubertus; Hernandez, Felix; White, Jason; Gerber, Cobus Wiley (2018-08-20)New psychoactive substances (NPS) have increased in use and popularity worldwide. Wastewater analysis has been successfully applied to evaluate illicit drugs use within a population. However, for NPS, such an approach may ... -
Investigation of pharmaceuticals and illicit drugs in waters by liquid chromatography-high-resolution mass spectrometry
Hernandez, Felix; Ibáñez, Maria; Bade, Richard; Bijlsma, Lubertus; Sancho, Juan V Elsevier (2014)Mass spectrometry (MS) coupled to chromatography has been increasingly used in the environmental field, as it allows the best performance currently attainable for the investigation of a wide range of organic pollutants. ... -
LC-QTOF MS screening of more than 1,000 licit and illicit drugs and their metabolites in wastewater and surface waters from the area of Bogotá, Colombia
Hernandez, Felix; Ibáñez, Maria; Botero-Coy, Ana Maria; Bade, Richard; Bustos López, Martha Cristina; Rincón, Javier; Moncayo-Lasso, Alejandro; Bijlsma, Lubertus Springer (2015-08)A large screening of around 1,000 emerging contaminants, focused on licit and illicit drugs and their metabolites, has been made in urban wastewaters (both influent and effluent) and surface waters from the area of Bogotá, ... -
Liquid chromatography-tandem mass spectrometry determination of synthetic cathinones and phenethylamines in influent wastewater of eight European cities
Bade, Richard; Bijlsma, Lubertus; Sancho, Juan V; Baz Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; GRACIA LOR, EMMA; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Hernandez, Felix Elsevier (2017)The popularity of new psychoactive substances (NPS) has grown in recent years, with certain NPS commonly and preferentially consumed even following the introduction of preventative legislation. With the objective to improve ... -
Liquid chromatography-tandem mass spectrometry determination of synthetic cathinones and phenethylamines in influent wastewater of eight European cities
Bade, Richard; Bijlsma, Lubertus; Sancho, Juan V; Baz Lomba, Jose Antonio; Castiglioni, Sara; Castrignanò, Erika; Causanilles, Ana; GRACIA LOR, EMMA; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; McCall, Ann-Kathrin; van Nuijs, Alexander; Ort, Christoph; Plosz, Benedek; Ramin, Pedram; Rousis, Nikolaos I; Ryu, Yeonsuk; Thomas, Kevin V.; de Voogt, Pim; Zuccato, Ettore; Hernandez, Felix Elsevier (2017-02)The popularity of new psychoactive substances (NPS) has grown in recent years, with certain NPS commonly and preferentially consumed even following the introduction of preventative legislation. With the objective to improve ... -
Measuring biomarkers in wastewater as a new source of epidemiological information: current state and future perspectives
GRACIA LOR, EMMA; Castiglioni, Sara; Bade, Richard; Been, Frederic; Castrignanò, Erika; Covaci, Adrian; González-Mariño, Iria; Hapeshi, Evroula; Kasprzyk-Hordern, Barbara; Kinyua, Juliet; Lai, Foon Yin; Letzel, Thomas; Lopardo, Luigi; Meyer, Markus R.; O'Brien, Jake; Ramin, Pedram; Rousis, Nikolaos I; Rydevik, Axel; Ryu, Yeonsuk; Santos, Miguel M.; Senta, Ivan; Thomaidis, Nikolaos; Veloutsou, Sofia; Yang, Zhugen; Zuccato, Ettore; Bijlsma, Lubertus Elsevier (2017-02)The information obtained from the chemical analysis of specific human excretion products (biomarkers) in urban wastewater can be used to estimate the exposure or consumption of the population under investigation to a defined ... -
Monitoring a large number of pesticides and transformation products in water samples from Spain and Italy
Rousis, Nikolaos I; Bade, Richard; Bijlsma, Lubertus; Zuccato, Ettore; Sancho, Juan V; Hernandez, Felix; Castiglioni, Sara Elsevier (2017-07)Assessing the presence of pesticides in environmental waters is particularly challenging because of the huge number of substances used which may end up in the environment. Furthermore, the occurrence of pesticide transformation ... -
Perspectives and challenges associated with the determination of new psychoactive substances in urine and wastewater – A tutorial
Bijlsma, Lubertus; Bade, Richard; Been, Frederic; Celma, Alberto; Castiglioni, Sara Elsevier (2021-02-08)New psychoactive substances (NPS), often designed as (legal) substitutes to conventional illicit drugs, are constantly emerging in the drug market and being commercialized in different ways and forms. Their use continues ... -
Prediction of Collision Cross-Section Values for Small Molecules: Application to Pesticide Residue Analysis
Bijlsma, Lubertus; Bade, Richard; Celma, Alberto; Mullin, Lauren; Cleland, Gareth; Stead, Sara; Hernandez, Felix; Sancho, Juan V (2017)The use of collision cross-section (CCS) values obtained by ion mobility high-resolution mass spectrometry has added a third dimension (alongside retention time and exact mass) to aid in the identification of compounds. ...