Listar por autoría "c2579bec-6c8d-4882-aaa4-ca7e9d308358"
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Paclitaxel Induces Epidermal Molecular Changes and Produces Subclinical Alterations in the Skin of Gynecological Cancer Patients
Montero, Paula; Pérez-Leal, Martín; Pérez-Fidalgo, J. Alejandro; Sanz, Celia; Estornut, Cristina; Roger, Inés; MILARA, JAVIER; Cervantes, Andrés; Cortijo, Julio MDPI (2022-03-01)Background: Paclitaxel is a microtubule-stabilizing chemotherapeutic agent. Despite its widespread use, it damages healthy tissues such as skin. The goal of this study was to prove that the real impact of paclitaxel-induced ... -
Paclitaxel-Induced Epidermal Alterations: An In Vitro Preclinical Assessment in Primary Keratinocytes and in a 3D Epidermis Model
Sanz, Celia; Montero, Paula; MILARA, JAVIER; Pérez-Leal, Martín; Estornut, Cristina; Roger, Inés; Pérez-Fidalgo, J. Alejandro; Cortijo, Julio MDPI (2022-01-22)Paclitaxel is a microtubule-stabilizing chemotherapeutic agent approved for the treatment of ovarian, non-small cell lung, head, neck, and breast cancers. Despite its beneficial effects on cancer and widespread use, ...