Listar por autoría "6fa6ea94-2913-4d3f-822d-7945d51ac80a"
Mostrando ítems 1-14 de 14
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Childhood abuse in the etiological continuum underlying psychosis from first-episode psychosis to psychotic experiences
Alemany, Silvia; Ayesa-Arriola, R.; Arias, Barbara; Fatjó-Vilas, Mar; Ibáñez, Manuel I; Ortet, Generós; Crespo-Facorro, B.; Fañanás Saura, Lourdes Elsevier (2015)Goal The present study aimed to examine the prevalence of child abuse across the continuum of psychosis. Patients and methods The sample consisted of 198 individuals divided in three groups: (1) 48 FEP patients, ... -
Childhood abuse, the BDNF-Val66Met polymorphism and adult psychotic-like experiences
Alemany, Silvia; Arias, Barbara; Aguilera, Mari; Villa Martín, Elena; Moya-Higueras, Jorge; Ibáñez, Manuel I; Vossen, Helen; Gastó, Cristóbal; Ortet, Generós; Fañanás Saura, Lourdes The Royal College of Psychiatrists (2011)Individuals exposed to childhood abuse are more likely to report positive psychotic-like experiences. Met carriers reported more positive psychotic-like experiences when exposed to childhood abuse than did individuals ... -
Childhood trauma and the rs1360780 SNP of FKBP5 gene in psychosis: a replication in two general population samples
Alemany, Silvia; Moya, Jorge; Ibáñez, Manuel I; Villa Martín, Elena; Mezquita, Laura; Ortet, Generós; Gastó, Cristóbal; Fañanás Saura, Lourdes; Arias, Barbara Cambridge University Press (2016)FKBP5 gene interacts with childhood trauma in the risk for several stress-related psychiatric disorders including subclinical psychosis. The present study examined whether variation at the rs1360780 SNP of FKBP5 gene ... -
Early adversity and 5-HTT-BDNF genes: new evidences of gene-environment interactions on depressive symptoms in a general population
Aguilera, Mari; Arias, Barbara; Wichers, Marieke; Barrantes Vidal, Neus; Moya-Higueras, Jorge; Villa Martín, Elena; Van Os, Jim; Ibáñez, Manuel I; Ruipérez Rodríguez, María Ángeles; Ortet, Generós; Fañanás Saura, Lourdes Cambridge University Press (2009-09)Adverse childhood experiences have been described as one of the major environmental risk factors for depressive disorder. Likewise, the deleterious impact of early traumatic experiences on depression seems to be moderated ... -
Evidence of an epistatic effect between Dysbindin-1 and Neuritin-1 genes on the risk for schizophrenia spectrum disorders
Prats, Claudia; Arias, Barbara; Moya-Higueras, Jorge; Pomarol Clotet, Edith; Parellada, Mara; González Pinto, Ana; Peralta, Víctor; Ibáñez, Manuel I; Martín, M.; Fañanás Saura, Lourdes; Fatjó-Vilas, Mar Elsevier (2017-02)Background The interest in studying gene–gene interactions is increasing for psychiatric diseases such as schizophrenia-spectrum disorders (SSD), where multiple genes are involved. Dysbindin-1 (DTNBP1) and Neuritin-1 ... -
Psychometric properties of drinking motives questionnaire-revised (DMQ-R) in Spanish adolescents
Mezquita, Laura; Moya-Higueras, Jorge; Villa Martín, Elena; Ibáñez, Manuel I; Arias, Barbara; Fañanás Saura, Lourdes; Ortet, Generós Hogrefe (2016)The Drinking Motives Questionnaire-Revised (DMQ-R; Cooper, 1994) is the most widely used questionnaire to assess drinking motives. This research aimed to adapt and study the validity and reliability of the Spanish DMQ-R ... -
Psychosis-inducing effects of cannabis are related to both childhood abuse and COMT genotypes
Alemany, Silvia; Arias, Barbara; Fatjó-Vilas, Mar; Villa Martín, Elena; Moya-Higueras, Jorge; Ibáñez, Manuel I; Ortet, Generós; Gastó, Cristóbal; Fañanás Saura, Lourdes Wiley (2014-01)OBJECTIVE: To test whether the association between childhood abuse, cannabis use and psychotic experiences (PEs) was moderated by the COMT (catechol-O-methyltransferase) gene. METHOD: Psychotic experiences (PEs), ... -
Putative role of the COMT gene polymorphism (Val158Met) on verbal working memory functioning in a healthy population
Aguilera, Mari; Barrantes Vidal, Neus; Arias, Barbara; Moya-Higueras, Jorge; Ibáñez, Manuel I; Ruipérez Rodríguez, María Ángeles; Ortet, Generós; Fañanás Saura, Lourdes John Wiley & Sons (2008)Working memory has been described as a neurocognitive probe of prefrontal brain functioning. Genetic variability related with catechol-O-methyltransferase (COMT) gene (Val158Met polymorphism) has received increasing attention ... -
Role of neurotrophins in depressive symptoms and executive function: Association analysis of NRN1 gene and its interaction with BDNF gene in a non-clinical sample
Prats, Claudia; Arias, Barbara; Ortet, Generós; Ibáñez, Manuel I; Moya-Higueras, Jorge; Pomarol Clotet, Edith; Fañanás Saura, Laura; Fatjó-Vilas, Mar Elsevier (2016-11)Background Neuritin-1 is a neurotrophic factor involved in synaptic plasticity that has been associated with depressive disorders, schizophrenia and cognitive performance. The study of genotype-phenotype relationships ... -
Season of birth and subclinical psychosis: systematic review and meta-analysis of new and existing data (Review)
Córdova-Palomera, Aldo; Calati, Raffaella; Arias, Barbara; Ibáñez, Manuel I; Moya, Jorge; Ortet, Generós; Crespo-Facorro, B.; Fañanás Saura, Lourdes Elsevier (2015)Season of birth (SOB) has been shown to modify the risk of several health outcomes, including a number of neuropsychiatric disorders. Empirical evidence indicates that subclinical forms of psychosis in the general population ... -
The effect of the AKT1 gene and cannabis use on cognitive performance in healthy subjects
Fatjó-Vilas, Mar; Soler, Jordi; Ibáñez, Manuel I; Moya-Higueras, Jorge; Ortet, Generós; Guardiola-Ripoll, M.; Fañanás Saura, Lourdes; Arias, Barbara Sage (2020-06-13)Background: Evidence suggests that the AKT1 gene may modulate the degree to which cannabis use induces cognitive alterations in patients with a psychotic disorder. Aim: To examine the interplay between AKT1 and cannabis ... -
The interaction between the ZNF804A gene and cannabis use on the risk of psychosis in a non-clinical sample
Soler, Jordi; Arias, Barbara; Moya, Jorge; Ibáñez, Manuel I; Ortet, Generós; Fañanás Saura, Lourdes; Fatjó-Vilas, Mar Elsevier (2019)The ZNF804A gene and cannabis use are risk factors for psychosis and both have also been associated with schizotypal traits. This study aimed to investigate: i) the association of lifetime cannabis use (and its dose ... -
The role of genetic variability in the GABRA6, 5-HTT and BDNF genes in anxiety-related traits
Villa Martín, Elena; Ibáñez, Manuel I; Ortet, Generós; Arias, Barbara; Aguilera, Mari; Moya-Higueras, Jorge; Sáiz Martínez, Pilar Alejandra; García-Portilla González, María Paz, 1962-; Bobes García, Julio; Fañanás Saura, Lourdes Wiley-Blackwell (2012-03)Objective: The aims of this study were to test the individual association of the serotonin transporter gene (SLC6A4), the brain-derived neurotrophic factor gene (BDNF) and the GABAAα6 receptor subunit gene (GABRA6) with ... -
Violent aggression predicted by multiple pre-adult environmental hits
Mitjans, Marina; Seidel, Jan; Begemann, Martin; Bockhop, Fabian; Moya-Higueras, Jorge; Bansal, Vikas; Wesolowsk, Janina; Seelbach, Anna; Ibáñez, Manuel I; Kovacevic, Fatka; Duvar, Oguzhan; Fañanás Saura, Lourdes; Wolf, Hannah-Ulrike; Ortet, Generós; Zwanzger, Peter; Klein, Verena; Lange, Ina; Tänzer, Andreas; Dudeck, Manuela; Penke, Lars; Tebartz van Elst, Ludger; Bittner, Robert A.; Schmidmeier, Richard; Freese, Roland; Müller-Isberner, Rüdiger; Wiltfang, Jens; Bliesener, Thomas; Bonn, Stefan; Poustka, Luise; Müller, Jürgen L.; Arias, Barbara; Ehrenreich, Hannelore Nature Publishing Group (2018)Early exposure to negative environmental impact shapes individual behavior and potentially contributes to any mental disease. We reported previously that accumulated environmental risk markedly decreases age at schizophrenia ...