Listar por autoría "639c9bad-0cb7-456c-83e7-7bbea73406e3"
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Caffeine Modulates Food Intake Depending on the Context That Gives Access to Food: Comparison With Dopamine Depletion
Correa, Merce; San Miguel Segura, Noemí; López Cruz, Laura; Carratalá-Ros, Carla; Olivares-García, Régulo; Salamone, John (2018-09-06)Caffeine is a methylxanthine consumed in different context s to potentiate alertness and reduce fatigue. However, caffeine can induce anxiety at hig h doses. Caffeine is also a minor psychostimulant that seems to act ... -
Complexities and paradoxes in understanding the role of dopamine in incentive motivation and instrumental action: Exertion of effort vs. anhedonia
Salamone, John; Ecevitoglu, Alev; Carratalá-Ros, Carla; Presby, Rose; Edelstein, Gayle A; Fleeher, Reileigh; Rotolo, Renee; Meka, Nicolette; Srinath, Sonya; Masthay, Jamie C.; Correa, Merce Elsevier (2022-05)Instrumental behavior is a very complex and multifaceted process. Behavioral output during instrumental performance is influenced by a variety of factors, including associative conditioning, directional and activational ... -
Dopamine depletion shifts behavior from activity based reinforcers tomore sedentary ones and adenosine receptor antagonism reversesthat shift: Relation to ventral striatum DARPP32 phosphorylationpatterns
López Cruz, Laura; SanMiguel, Noemí; Carratalá-Ros, Carla; Monferrer Sales, Lidón; Salamone, John; Correa, Merce Elsevier (2018)The mesolimbic dopamine (DA) system plays a critical role in behavioral activation and effort-baseddecision-making. DA depletion produces anergia (shifts to low effort options) in animals tested oneffort-based decision-making ... -
Efecto de la modulación dopaminérgica en la preferencia por reforzadores activos en ratones con una mutación en el factor de transcripción Pitx3
Verdejo-Penyarrocha, Mireia; Martínez-Verdú, Andrea; Olivares-García, Régulo; Matas-Navarro, Paula; Carratalá-Ros, Carla Publicacions de la Universitat Jaume I. Servei de Comunicació i Publicacions (2022)La conducta motivada está caracterizada por altos niveles de activación, vigor y persistencia. La dopamina del núcleo accumbens (nacb) está implicada en regular este componente energizante de la motivación, incluida la ... -
Effects of the dopamine depleting agent tetrabenazine in tests evaluating different components of depressive-like behavior in mice : sex-dependent response to antidepressant drugs with SERT and DAT blocker profiles
Carratalá Ros, Carla; Martínez‑Verdú, Andrea; Olivares-García, Régulo; Salamone, John; Correa, Merce Springer Nature (2023-07-05)Background ; Depression is a disorder twice as common in women than in men. There are sex differences in the symptomatology and treatment response to this disorder. Impairments in behavioral activation (i.e. anergia, ... -
Effects of the dopamine depleting agent tetrabenazine on detailed temporal parameters of effort-related choice responding
Ren, Naxin; Carratalá-Ros, Carla; Ecevitoglu, Alev; Rotolo, Renee; Edelstein, Gayle A; Presby, Rose; Stevenson, Ian; Chrobak, James; Salamone, John Society for the Experimental Analysis of Behavior (2022-03-28)The dopamine-depleting agent tetrabenazine alters effort-based choice, suppressing food-reinforced behaviors with high response requirements, while increasing selection of low-cost options. In the present experiments, rats ... -
Energizing effects of bupropion on effortful behaviors in mice under positive and negative test conditions: modulation of DARPP-32 phosphorylation patterns
Carratalá-Ros, Carla; Olivares-García, Régulo; Martínez-Verdú, Andrea; Arias-Sandoval, Edgar; Salamone, John; Correa, Merce Springer (2021-09-09)Motivational symptoms such as anergia, fatigue, and reduced exertion of effort are seen in depressed people. To model this, nucleus accumbens (Nacb) dopamine (DA) depletions are used to induce a low-effort bias in rodents ... -
Enfermedad de Parkinson: progresión de la enfermedad a nivel neuroanatómico y funcional. Revisión Bibliográfica
Carratalá-Ros, Carla (2014-06)La enfermedad de Parkinson es la segunda enfermedad neurodegenerativa más conocida mundialmente, después de la enfermedad de Alzheimer. Afecta actualmente al 1%-2% de la población de 65 años y al 3%-5% de la población de ... -
Impact of Caffeine on Ethanol‐Induced Stimulation and Sensitization: Changes in ERK and DARPP‐32 Phosphorylation in Nucleus Accumbens
Porru, Simona; López Cruz, Laura; Carratalá-Ros, Carla; Salamone, John; Acquas, Elio; Correa, Merce Wiley (2021)Background: Caffeine is frequently consumed with ethanol to reduce the impairing effects induced by ethanol, including psychomotor slowing or incoordination. Both drugs modulate dopamine (DA)‐related markers in accumbens ... -
Impact of Fluoxetine on Behavioral Invigoration of Appetitive and Aversively Motivated Responses: Interaction With Dopamine Depletion
Carratalá-Ros, Carla; López Cruz, Laura; Martínez Verdú, Andrea; Olivares-García, Régulo; Salamone, John; Correa, Merce Frontiers Media (2021)Impaired behavioral activation and effort-related motivational dysfunctions like fatigue and anergia are debilitating treatment-resistant symptoms of depression. Depressed people show a bias towards the selection of low ... -
Individual differences in the energizing effects of caff eine on effort-baseddecision-making tests in rats
SanMiguel, Noemí; Pardo, Marta; Carratalá-Ros, Carla; López Cruz, Laura; Salamone, John; Correa, Merce Elsevier (2018)Motivated behavior is characterized by activation and high work output. Nucleus accumbens (Nacb) modulates behavioral activation and effort-based decision-making. Caffeine is widely consumed because of its energizing ... -
Preference for Exercise vs. More Sedentary Reinforcers: Validation of an Animal Model of Tetrabenazine-Induced Anergia
Carratalá-Ros, Carla; López Cruz, Laura; San Miguel Segura, Noemí; Ibáñez-Marín, Patricia; Martínez Verdú, Andrea; Salamone, John; Correa, Merce Frontiers Media (2020-01-30)Physical activities can have intrinsic motivational or reinforcing properties. The choice to engage in voluntary physical activity is undertaken in relation to the selection of other alternatives, such as sedentary ... -
Sex and age differences in mice models of effort-based decision-making and anergia in depression : the role of dopamine, and cerebral-dopamine-neurotrophic-factor
Matas-Navarro, Paula; Carratalá Ros, Carla; Olivares-García, Régulo; Martínez-Verdú, Andrea; Salamone, John; Correa, Merce Springer Nature (2023-08-18)Mesolimbic dopamine (DA) regulates vigor in motivated behavior. While previous results have mainly been performed in male rodents, the present studies compared CD1 male and female mice in effort-based decision-making tests ... -
Sex differences in lever pressing and running wheel tasks of effort-based choice behavior in rats: Suppression of high effort activity by the serotonin transport inhibitor fluoxetine
Presby, Rose; Rotolo, Renee; Hurley, Erin M.; Ferrigno, Sarah M.; Murphy, Cayla; McMullen, Haley P.; Desai, Pranally A.; Zorda, Emma; Kuperwasser, Felicita B.; Carratalá-Ros, Carla; Correa, Merce; Salamone, John Elsevier (2021)Selective serotonin transport (SERT) inhibitors such as fluoxetine are the most commonly prescribed treatments for depression. Although efficacious for many symptoms of depression, motivational impairments such as psychomotor ...