Listar por autoría "54993a6c-3855-4e39-b10e-6019d88ba3c9"
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Amino acid change in the carbohydrate response element binding protein is associated with lower triglycerides and myocardial infarction incidence depending on level of adherence to the Mediterranean diet in the PREDIMED trial
CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; Estruch, Ramon; Asensio, Eva Maria; Coltell, Oscar; González, José I.; Martínez González, Miguel Ángel; Ros, Emilio; Salas-Salvadó, Jordi; Fitó, Montserrat; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Ruiz-Gutiérrez, Valentina; Gómez Gracia, Enrique; Fiol Ramis, Miquel; Flores, Gemma; Pintó, Xavier; Sáiz, Carmen; Ordovás Muñoz, José M.; Corella, Dolores American Heart Association (2014-02)Background: A variant (rs3812316, C771G, Gln241His) in the MLXIPL (Max-like protein X interacting protein-like) gene encoding the carbohydrate response element binding protein has been associated with lower triglycerides. ... -
Association between dietary fibre intake and fruit, vegetable or whole-grain consumption and the risk of CVD: results from the PREvención con DIeta MEDiterránea (PREDIMED) trial
Buil-Cosiales, Pilar; Toledo, Estefanía; Salas-Salvadó, Jordi; Zazpe, Itziar; Farràs, Marta; Basterra-Gortari, Francisco Javier; Díez Espino, Javier; Estruch, Ramon; Corella, Dolores; Ros, Emilio; Marti, Amelia; Gómez Gracia, Enrique; Ortega-Calvo, Manuel; Arós, Fernando; Moñino, Manuel; Serra-Majem, Lluis; Pintó, Xavier; Lamuela Raventós, Rosa María; Babio, Nancy; González, José I.; Fitó, Montserrat; Martínez González, Miguel Ángel Nutrition Society (2016)Prospective studies assessing the association between fibre intake or fibre-rich food consumption and the risk of CVD have often been limited by baseline assessment of diet. Thus far, no study has used yearly repeated ... -
Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulate by diet, being higher when adherence to the Mediterranean diet pattern is low
Coltell, Oscar; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Gómez Gracia, Enrique; Fiol Ramis, Miquel; Sáez Tormo, Guillermo; Pintó, Xavier; Muñoz, Miguel Ángel; Ordovás Muñoz, José M.; Estruch, Ramon; Corella, Dolores; CAROLINA, ORTEGA-AZORÍN; Sorlí, José V; Asensio, Eva Maria; Covas Planells, María Isabel; Ros, Emilio BioMed Central (2012-11)Background: Although the Fat Mass and Obesity (FTO) and Melanocortin-4 Receptor (MC4R) genes have been consistently associated with obesity risk, the association between the obesity-risk alleles with type 2 diabetes is ... -
Associations of the MCM6-rs3754686 proxy for milk intake in Mediterranean and American populations with cardiovascular biomarkers, disease and mortality: Mendelian randomization
Smith, C.E.; Coltell, Oscar; Sorlí, José V; Estruch, Ramon; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Fitó, Montserrat; Arós, Fernando; Dashti, Hassan S.; Lai, Chao-Qiang; Miró, Leticia; Serra-Majem, Lluis; Gómez Gracia, Enrique; Fiol Ramis, Miquel; Ros, Emilio; Aslibekyan, Stella; Hidalgo, Bertha; Neuhouser, Marian L.; Di, Chongzhi; Tucker, Katherine; Arnett, Donna K.; Ordovás Muñoz, José M.; Corella, Dolores Nature Publishing Group (2016)Controversy persists on the association between dairy products, especially milk, and cardiovascular diseases (CVD). Genetic proxies may improve dairy intake estimations, and clarify diet-disease relationships through ... -
CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial
Corella, Dolores; Asensio, Eva Maria; Coltell, Oscar; Sorlí, José V; Estruch, Ramon; Martínez González, Miguel Ángel; Castañer, Olga; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Gómez Gracia, Enrique; CAROLINA, ORTEGA-AZORÍN; Fiol Ramis, Miquel; Díez Espino, Javier; Díaz López, Andrés; Fitó, Montserrat; Ros, Emilio; Ordovás Muñoz, José M. BioMed Central (2016-01)Background Circadian rhythms regulate key biological processes influencing metabolic pathways. Disregulation is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). Circadian rhythms are generated by ... -
Intake of Total Polyphenols and Some Classes of Polyphenols Is Inversely Associated with Diabetes in Elderly People at High Cardiovascular Disease Risk
Tresserra-Rimbau, Anna; Guash-Ferré, Marta; Salas-Salvadó, Jordi; Toledo, Estefanía; Corella, Dolores; Castañer, Olga; Guo, Xiaohui; Gómez Gracia, Enrique; Lapetra, José; Arós, Fernando; Fiol Ramis, Miquel; Ros, Emilio; Serra-Majem, Lluis; Pintó, Xavier; Fitó, Montserrat; Babio, Nancy; Martínez González, Miguel Ángel; Sorlí, José V; López-Sabater, Maria Carmen; Estruch, Ramon; Lamuela Raventós, Rosa María; Coltell, Oscar; PREDIMED Investigators American Society for Nutrition (2016-03)Background: Higher consumption of some polyphenols has been associated with a reduced risk of diabetes. However, no studies have evaluated the relation between all polyphenol subclasses and the incidence of diabetes. Objective: ... -
Inverse association between habitual polyphenol intake and incidence of cardiovascular events in the PREDIMED study
Tresserra-Rimbau, Anna; Rimm, Eric B.; Medina Remón, A.; Martínez González, Miguel Ángel; De la Torre, R.; Corella, Dolores; Salas-Salvadó, Jordi; Gómez Gracia, Enrique; Lapetra, José; Arós, Fernando; Fiol Ramis, Miquel; Ros, Emilio; Serra-Majem, Lluis; Pintó, Xavier; Sáez Tormo, Guillermo; Basora, Josep; Sorlí, José V; Martínez, J. Alfredo; Vinyoles, E.; Ruiz-Gutiérrez, Valentina; Estruch, Ramon; Lamuela Raventós, Rosa María; Coltell, Oscar Elsevier (2016-06)Background and aims Epidemiologic and biological evidence supports an inverse association between polyphenol consumption and the risk of cardiovascular disease (CVD). However, no previous studies have prospectively ... -
Mediterranean Diet Reduces the Adverse Effect of the TCF7L2-rs7903146 Polymorphism on Cardiovascular Risk Factors and Stroke Incidence
Corella, Dolores; Carrasco, Paula; Sorlí, José V; Estruch, Ramon; Rico Sanz, Jesús; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Covas Planells, María Isabel; Coltell, Oscar; Arós, Fernando; Lapetra, José; Serra-Majem, Lluis; Ruiz-Gutiérrez, Valentina; Warnberg, Julia; Fiol Ramis, Miquel; Pintó, Xavier; CAROLINA, ORTEGA-AZORÍN; Muñoz, Miguel Ángel; Martínez, J. Alfredo; Gómez Gracia, Enrique; González, José I.; Ros, Emilio; Ordovás Muñoz, José M. American Diabetes Association (2013)OBJECTIVE Transcription factor 7-like 2 (TCF7L2) polymorphisms are strongly associated with type 2 diabetes, but controversially with plasma lipids and cardiovascular disease. Interactions of the Mediterranean diet (MedDiet) ... -
Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial
Corella, Dolores; Sorlí, José V; González, José I.; CAROLINA, ORTEGA-AZORÍN; Fitó, Montserrat; Bulló, Mònica; Martínez González, Miguel Ángel; Ros, Emilio; Arós, Fernando; Lapetra, José; Gómez Gracia, Enrique; Serra-Majem, Lluis; Ruiz-Gutiérrez, Valentina; Fiol Ramis, Miquel; Coltell, Oscar; Vinyoles, Ernest; Pintó, Xavier; Martí, Amelia; Sáiz, Carmen; Ordovás Muñoz, José M.; Estruch, Ramon BioMed Central (2014-01)Background: The Fas apoptotic pathway has been implicated in type 2 diabetes and cardiovascular disease. Although a polymorphism (rs7138803; G > A) near the Fas apoptotic inhibitory molecule 2 (FAIM2) locus has been related ... -
Polymorphism of the Transcription Factor 7-Like 2 Gene (TCF7L2) Interacts with Obesity on Type-2 Diabetes in the PREDIMED Study Emphasizing the Heterogeneity of Genetic Variants in Type-2 Diabetes Risk Prediction: Time for Obesity-Specific Genetic Risk Scores
Corella, Dolores; Coltell, Oscar; Sorlí, José V; Estruch, Ramon; Quiles Guiñau, Laura; Martínez González, Miguel Ángel; Salas-Salvadó, Jordi; Castañer, Olga; Arós, Fernando; Ortega-Calvo, Manuel; Serra-Majem, Lluis; Gómez Gracia, Enrique; Portolés, Olga; Fiol Ramis, Miquel; Díez Espino, Javier; Basora, Josep; Fitó, Montserrat; Ros, Emilio; Ordovás Muñoz, José M. MDPI (2016)Nutrigenetic studies analyzing gene–diet interactions of the TCF7L2-rs7903146 C > T polymorphism on type-2 diabetes (T2D) have shown controversial results. A reason contributing to this may be the additional modulation by ...