Listar por autoría "12230843-9d8f-4b45-a692-d9e50c3c9630"
Mostrando ítems 1-20 de 23
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Analytical strategy to investigate 3,4-methylenedioxypyrovalerone (MDPV) metabolites in consumers’ urine by high-resolution mass spectrometry
Ibáñez, Maria; Pozo, Óscar J.; Sancho, Juan V; Orengo, Teresa; Haro, Gonzalo; Hernandez, Felix Springer (2016-01)The potential of high-resolution mass spectrometry (HRMS) for the investigation of human in vivo metabolism of 3,4-methylenedioxypyrovalerone (MDPV) using urine collected from a consumer (this is, in non-controlled ... -
Capabilities of microbore columns coupled to inductively coupled plasma mass spectrometry in speciation of arsenic and selenium
Castillo Tirado, Ángel; Roig-Navarro, Antoni F.; Pozo, Óscar J. Elsevier (2008)The performance of microHPLC-microconcentric nebulizer-inductively coupled plasma-mass spectrometry (ICP-MS) coupling for the simultaneous determination of As(III), As(V), monomethylarsenic acid (MMA), dimethylarsinic acid ... -
Comparison between triple quadrupole, time of flight and hybrid quadrupole time of flight analysers coupled to liquid chromatography for the detection of anabolic steroids in doping control analysis
Pozo, Óscar J.; Van Eenoo, Peter; Deventer, Koen; Elbardissy, Hisham; Grimalt Brea, Susana; Sancho, Juan V; Hernandez, Felix; Ventura, Rosa; Delbeke, Frans T. Elsevier (2011-01-17)Triple quadrupole (QqQ), time of flight (TOF) and quadrupole-time of flight (QTOF) analysers have been compared for the detection of anabolic steroids in human urine. Ten anabolic steroids were selected as model compounds ... -
Detection and Characterization of a New Metabolite of 17α-Methyltestosterone
Pozo, Óscar J.; Van Eenoo, Peter; Deventer, Koen; Lootens, Leens; Van Thuyne, Wim; Parr, Maria K.; Schänzer, Wilhelm; Sancho, Juan V; Hernandez, Felix; Meuleman, Philip; Leroux-Roels, Geert; Delbeke, Frans T. The American Society for Pharmacology and Experimental Therapeutics (2009-11)The misuse of the anabolic steroid methyltestosterone is currently routinely monitored in doping control laboratories by gas chromatography-mass spectrometry (GC-MS) of two of its metabolites: 17α-methyl-5β-androstane-3α,17β-diol ... -
Detection and characterization of anabolic steroids in doping analysis by LC-MS
Pozo, Óscar J.; Van Eenoo, Peter; Deventer, Koen; Delbeke, Frans T. Elsevier (2008)The detection of target anabolic steroids in doping analysis has generally been performed by gas chromatography combined with mass spectrometry (GC-MS). However, liquid chromatography combined with tandem mass spectrometry ... -
Detection and structural investigation of metabolites of stanozolol in human urine by liquid chromatography tandem mass spectrometry
Pozo, Óscar J.; Van Eenoo, Peter; Deventer, Koen; Lootens, Leens; Grimalt Brea, Susana; Sancho, Juan V; Hernandez, Felix; Meuleman, Philip; Leroux-Roels, Geert; Delbeke, Frans T. Elsevier (2009)The applicability of LC-MS/MS in precursor ion scan mode for the detection of urinary stanozolol metabolites has been studied. The product ion at m/z 81 has been selected as specific for stanozolol metabolites without a ... -
Determination of selected endogenous anabolic androgenic steroids and ratios in urine by ultra high performance liquid chromatography tandem mass spectrometry and isotope pattern deconvolution
Pitarch-Motellón, Jorge; Sancho, Juan V; Ibáñez, Maria; Pozo, Óscar J.; Roig-Navarro, Antoni F. Elsevier (2017-09)An isotope dilution mass spectrometry (IDMS) method for the determination of selected endogenous anabolic androgenic steroids (EAAS) in urine by UHPLC–MS/MS has been developed using the isotope pattern deconvolution (IPD) ... -
Direct quantification of steroid glucuronides in human urine by liquid chromatography-electrospray tandem mass spectrometry
Pozo, Óscar J.; Van Eenoo, Peter; Van Thuyne, Wim; Deventer, Koen; Delbeke, Frans T. Elsevier (2008)A method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the direct quantification of glucuronides of testosterone (TG), epitestosterone (EPG), androsterone (AG) and etiocholanolone (ETG) has been ... -
Evaluation of uncertainty sources in the determination of testosterone in urine by calibration-based and isotope dilution quantification using ultra high performance liquid chromatography tandem mass spectrometry
Pitarch-Motellón, Jorge; Roig-Navarro, Antoni F.; Sancho, Juan V; Ibáñez, Maria; Fabregat-Cabello, Neus; Pozo, Óscar J.; Ventura, Rosa; García Alonso, J. Ignacio; Rodríguez González, Pablo; González Gago, Adriana; Ereño Artabe, Amaia; Van Eenoo, Peter; Deventer, Koen; Dehnes, Yvette; Rzeppa, Sebastian Elsevier (2017-06)Three quantification methodologies, namely calibration with internal standard (Cal-IS, non-weighted), weighted calibration with internal standard (wCal-IS) and isotope pattern deconvolution (IPD) have been used for the ... -
Investigating the presence of pesticide transformation products in water by using liquid chromatography-mass spectrometry with different mass analyzers
Hernandez, Felix; Ibáñez, Maria; Pozo, Óscar J.; Sancho, Juan V John Wiley & Sons (2008)Many pesticide transformation products (TPs) can reach environmental waters as a consequence of their normally having a higher polarity than their parent pesticides. This makes the development of analytical methodology ... -
Isotope Dilution LC-ESI-MS/MS and low resolution Selected Reaction Monitoring as a tool for the accurate quantification of urinary testosterone
Ereño Artabe, Amaia; Gonzalez-Gago, Adriana; Suarez Fernández, Amanda; Pitarch-Motellón, Jorge; Roig-Navarro, Antoni F.; Pozo, Óscar J.; Rodríguez González, Pablo; García Alonso, J. Ignacio Elsevier (2018-09)A new analytical method for the quantification of testosterone in human urine samples by isotope dilution mass spectrometry is proposed. A standard solution of 13C2-testosterone is added to the samples at the beginning of ... -
Mass spectrometric behavior of anabolic androgenic steroids using gas chromatography coupled to atmospheric pressure chemical ionization source. Part I: Ionization
Raro Macián, Montserrat; Portoles, Tania; Sancho, Juan V; Pitarch, Elena; Hernandez, Felix; Marcos, Josep; Ventura, Rosa; Gómez, C.; Segura, Jordi; Pozo, Óscar J. John Wiley & Sons (2014-05)The detection of anabolic androgenic steroids (AAS) is one of the most important topics in doping control analysis. Gas chromatography coupled to (tandem) mass spectrometry (GC–MS(/MS)) with electron ionization and liquid ... -
Mass spectrometric characterisation of a condensation product between porphobilinogen and indolyl-3-acryloylglycine in urine of patients with acute intermittent porphyria
Marcos, Josep; Ibáñez, Maria; Ventura, Rosa; Segura, Jordi; To-Figueras, Jordi; Pozo, Oscar J. Wiley (2015-07)We document the presence of a previously unknown species in the urine of patients with acute intermittent porphyria (AIP). The compound was fully characterised by liquid chromatography tandem mass spectrometry. Interpretation ... -
Mass spectrometric characterisation of acondensation product betweenporphobilinogen and indolyl-3-acryloylglycinein urine of patients with acuteintermittent porphyria
Ibáñez, Maria; Marcos, Josep; Ventura, Rosa; Segura, Jordi; Pozo, Óscar J.; To-Figueras, Jordi Wiley (2015-07)We document the presence of a previously unknown species in the urine of patients with acute intermittent porphyria (AIP). Thecompound was fully characterised by liquid chromatography tandem mass spectrometry. Interpretation ... -
Mass spectrometric characterization of urinary toremifene metabolites for doping control analyses.
Hernandez, Felix; Díaz San Pedro, Ramón; Sancho, Juan V; Gómez, C.; Pozo, Óscar J.; Vilaroca, Enrique; Salvador, Jhon P; Marco, M. P.; Segura, Jordi; Ventura, Rosa © 2011 Elsevier (2011-07)Toremifene is a selective estrogen receptor modulator included in the list of prohibited substances in sport by the World Anti-doping Agency. The aim of the present study was to investigate toremifene metabolism in humans ... -
Mass Spectrometric Evaluation of Mephedrone In Vivo Human Metabolism: Identification of Phase I and Phase II Metabolites, Including a Novel Succinyl Conjugate
Pozo, Óscar J.; Ibáñez, Maria; Sancho, Juan V; Lahoz-Beneytez, Julio; Farré, Magi; Papaseit, Esther; De la Torre, Rafael; Hernandez, Felix American Society for Pharmacology and Experimental Therapeutics (ASPET) (2015-02)In recent years, many new designer drugs have emerged, including the group of cathinone derivatives. One frequently occurring drug is mephedrone; although mephedrone was originally considered as a “legal high” product, it ... -
Metabolomic approaches for orange origin discrimination by ultra-high performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry
Díaz, Ramon; Pozo, Óscar J.; Sancho, Juan V; Hernandez, Felix Elsevier (2014)In this work, hybrid quadrupole time-of-flight mass spectrometer (QTOF MS) coupled to ultra high performance liquid chromatography (UHPLC) has been used for biomarkers identification for correct authentication of Valencia ... -
Pesticide residues and transformation products in groundwater from a Spanish agricultural region on the Mediterranean Coast
Hernandez, Felix; Marín Ramos, José Manuel; Pozo, Óscar J.; Sancho, Juan V; Lopez, Francisco; Morell, Ignacio Taylor & Francis (2008)An overview is given on the presence and changes over time of pesticide residues in groundwater from the Valencia region, one of the most important citrus cultivation sites of southern Europe. A multiresidue LC-MS/MS ... -
Potential of atmospheric pressure chemical ionization source in gas chromatography tandem mass spectrometry for the screening of urinary exogenous androgenic anabolic steroids
Raro Macián, Montserrat; Portoles, Tania; Pitarch, Elena; Sancho, Juan V; Hernandez, Felix; Garrostas, L.; Marcos, Josep; Ventura, Rosa; Segura, Jordi; Pozo, Óscar J. Elsevier (2016-02-04)The atmospheric pressure chemical ionization (APCI) source for gas chromatography-mass spectrometry analysis has been evaluated for the screening of 16 exogenous androgenic anabolic steroids (AAS) in urine. The sample ... -
Quantification, confirmation and screening capability of UHPLC coupled to triple quadrupole and hybrid quadrupole time-of-flight mass spectrometry in pesticide residue analysis
Grimalt Brea, Susana; Sancho, Juan V; Pozo, Óscar J.; Hernandez, Felix John Wiley & Sons (2010-04)The potential of three mass spectrometry (MS) analyzers (triple quadrupole, QqQ; time of flight, TOF; and quadrupole time of flight, QTOF) has been investigated and compared for quantification, confirmation and screening ...