Iodine Supplementation During Pregnancy and Infant Neuropsychological: INMA Mother and Child Cohort Study
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Other documents of the author: Rebagliato, Marisa; Murcia, Mario; Álvarez Pedrerol, Mar; Espada, Mercedes; Fernández Somoano, Ana; Lertxundi, Nerea; Navarrete-Muñoz, Eva María; Forns, Joan; Aranbarri, Aritz; Llop, Sabrina; Julvez, Jordi; Tardon, Adonina; Ballester, Ferran
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http://dx.doi.org/10.1093/aje/kws333 |
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Title
Iodine Supplementation During Pregnancy and Infant Neuropsychological: INMA Mother and Child Cohort StudyAuthor (s)
Date
2013-04Publisher
Oxford University PressBibliographic citation
REBAGLIATO, M.; MURCIA, M.; ÁLVAREZ PEDREROL, M.; ESPADA, M.; FERNÁNDEZ SOMOANO, A.; LERTXUNDI, N.; NAVARRETE MUÑOZ, E. M.; FORNS, J.; ARANBARRI, A.; LLOP, S.; JULVEZ, J.; TARDÓN, A.; BALLESTER, F. Iodine Supplementation During Pregnancy and Infant Neuropsychological: INMA Mother and Child Cohort Study. American Journal of Epidemiology Advance Access, v. 177, n. 9 (May 1, 2013), p. 944-953Type
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Abstract
Iodine supplementation during pregnancy is a common practice in developed countries. However, scant evidence is available regarding the safety and effectiveness of maternal iodine supplementation with regard to child ... [+]
Iodine supplementation during pregnancy is a common practice in developed countries. However, scant evidence is available regarding the safety and effectiveness of maternal iodine supplementation with regard to child neuropsychological development. We previously reported an inverse association between iodine supplementation and the psychomotor development of infants in a birth cohort from Valencia, Spain. In the present study, we assessed this association in a wider sample of mother and child pairs from 3 other regions in Spain. Neuropsychological development was assessed using the Bayley Scales of Infant Development in 1,519 infants (median age, 16 months) between 2006 and 2009. In multivariate analyses, maternal consumption of 150 μg/day or more of iodine from supplements was related to a 1.5-fold increase in the odds of a psychomotor score less than 85 (95% confidence interval: 0.8, 2.9) and to a 1.7-fold increase in the odds of a mental score less than 85 (95% confidence interval: 0.9, 3.0). Findings previously reported in the Valencia cohort were only partially verified. The results of the present study suggest that, at least in these regions, iodine supplementation does not improve infant neuropsychological development at 1 year of age. Further research is needed on the risks and benefits of supplementary iodine for both maternal thyroid function and child neurodevelopment. [-]
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American Journal of Epidemiology, v. 177, n. 9 (May 1, 2013)Rights
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