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Associations of the MCM6-rs3754686 proxy for milk intake in Mediterranean and American populations with cardiovascular biomarkers, disease and mortality: Mendelian randomization
(Nature Publishing Group, 2016)
Controversy persists on the association between dairy products, especially milk, and cardiovascular diseases (CVD). Genetic proxies may improve dairy intake estimations, and clarify diet-disease relationships through ...
Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects
(MDPI, 2018)
There is growing interest in relating taste perception to diet and healthy aging. However, there is still limited information on the influence of age, sex and genetics on taste acuity as well as on the relationship between ...
A Guide to Applying the Sex-Gender Perspective to Nutritional Genomics
(MDPI, 2019)
Precision nutrition aims to make dietary recommendations of a more personalized nature
possible, to optimize the prevention or delay of a disease and to improve health. Therefore,
the characteristics (including sex) of ...
Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population
(MDPI, 2019)
Although, for decades, increased serum bilirubin concentrations were considered a threatening sign of underlying liver disease and had been associated with neonatal jaundice, data from recent years show that bilirubin is ...
A High Dietary Glycemic Index Increases Total Mortality in a Mediterranean Population at High Cardiovascular Risk
(Public Library of Science, 2014)
Objective: Different types of carbohydrates have diverse glycemic response, thus glycemic index (GI) and glycemic load (GL)
are used to assess this variation. The impact of dietary GI and GL in all-cause mortality is ...
Ultra-Performance Liquid Chromatography-Ion Mobility Separation-Quadruple Time-of-Flight MS (UHPLC-IMS-QTOF MS) Metabolomics for Short-Term Biomarker Discovery of Orange Intake: A Randomized, Controlled Crossover Study
(MDPI, 2020)
A major problem with dietary assessments is their subjective nature. Untargeted
metabolomics and new technologies can shed light on this issue and provide a more complete
picture of dietary intake by measuring the profile ...
Amino acid change in the carbohydrate response element binding protein is associated with lower triglycerides and myocardial infarction incidence depending on level of adherence to the Mediterranean diet in the PREDIMED trial
(American Heart Association, 2014-02)
Background: A variant (rs3812316, C771G, Gln241His) in the MLXIPL (Max-like protein X interacting protein-like) gene encoding the carbohydrate response element binding protein has been associated with lower triglycerides. ...
Candidate Gene and Genome-Wide Association Studies for Circulating Leptin Levels Reveal Population and Sex-Specific Associations in High Cardiovascular Risk Mediterranean Subjects
(MDPI, 2019)
Leptin is a hormone crucial in the regulation of food intake and body-weight maintenance. However, the genes and gene variants that influence its plasma levels are still not well known. Results of studies investigating ...
Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial
(BioMed Central, 2014-01)
Background: The Fas apoptotic pathway has been implicated in type 2 diabetes and cardiovascular disease. Although a polymorphism (rs7138803; G > A) near the Fas apoptotic inhibitory molecule 2 (FAIM2) locus has been related ...
Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk
(MDPI, 2019)
Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in
turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective:
To assess the association between fat ...