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The effect of strontium incorporation into sol-gel biomaterials on their protein adsorption and cell interactions
(Elsevier, 2019-02-01)
It is known strontium can both inhibit the osteoclast formation and stimulate the osteoblast maturation, so biomaterials containing this element can favour bone structure stabilisation. The addition of Sr to biomaterials ...
Design of nanostructured siloxane-gelatin coatings: Immobilization strategies and dissolution properties
(Elsevier, 2018-02)
Owing to the outstanding service life of metallic prostheses, a substantial effort has been put into their surface modification to improve biocompatibility and reduce metallic ion diffusion. To satisfy these requirements, ...
Sol-gel coatings for metallic prosthesis from methyl-modified alkoxysilanes: balance between protection and bioactivation
(Elsevier, 2020)
The reported osteogenic properties of the hybrid silica sol-gel materials make these compositions perfect candidates for bone tissue engineering applications. The aim of this study was the synthesis and characterisation ...
Enhancement of plasma protein adsorption and osteogenesis of hMSCs by functionalized siloxane coatings for titanium implants
(Wiley, 2018-03)
A series of sol–gel derived silicon based coatings
were developed to improve the osseointegration of commer-
cial titanium dental implants. The osseointegration starts
with a positive interaction between the implant ...
Bioactive zinc-doped sol-gel coating modulates protein adsorption patterns and in vitro cell responses
(Elsevier, 2020-12-30)
Zinc is an essential element with an important role in stimulating the osteogenesis and mineralization and suppressing osteoclast differentiation. In this study, new bioactive ZnCl2-doped sol-gel materials were designed ...
Complement proteins regulating macrophage polarisation on biomaterials
(Elsevier, 2019-09-01)
One of the events occurring when a biomaterial is implanted in an host is the protein deposition onto its surface, which might regulate cell responses. When a biomaterial displays a compromised biocompatibility, distinct ...
Proteomic evaluation of human osteoblast responses to titanium implants over time
(WileyWiley Periodicals, 2022-08-30)
Titanium is widely used in bone prostheses due to its excellent biocompatibility and osseointegration capacity. To understand the effect of sandblasted acid-etched (SAE) Ti implants on the biological responses of human ...
A possible use of melatonin in the dental field: Protein adsorption andinvitrocell response on coated titanium
(Elsevier, 2020)
Melatonin (MLT) is widely known for regulating the circadian cycles and has been studied for its role in boneregeneration and inflammation. Its application as a coating for dental implants can condition the local ...
Synthesis of hybrid sol-gel materials and their biological evaluation with human mesenchymal stem cells
(Springer, 2013-03)
Surface engineering of biomaterials could promote the osseointegration of implants. In this work, two types of hybrid sol–gel materials were developed to stimulate cell attachment, proliferation and differentiation of ...
Characterization of magnesium doped sol-gel biomaterial for bone tissue regeneration: The effect of Mg ion in protein adsorption
(Elsevier, 2021-06-01)
Magnesium is the fourth most abundant element in the human body with a wide battery of functions in the maintenance of normal cell homeostasis. In the bone, this element incorporates in the hydroxyapatite structure and it ...