A theoretical study on the decomposition mechanism of artemisinin
Impacte
Scholar |
Altres documents de l'autoria: Moles Tena, Pamela; Oliva, Mónica; Safont Villarreal, Vicent Sixte
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Mostra el registre complet de l'elementcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7013
comunitat-uji-handle3:10234/8638
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http://dx.doi.org/10.1016/j.tet.2008.07.086 |
Metadades
Títol
A theoretical study on the decomposition mechanism of artemisininData de publicació
2008-09Editor
ElsevierISSN
0040-4020Cita bibliogràfica
Tetrahedron, 64, 40, p. 9448-9463Tipus de document
info:eu-repo/semantics/articleVersió de l'editorial
http://www.sciencedirect.com/science/article/pii/S0040402008013744Versió
info:eu-repo/semantics/publishedVersionParaules clau / Matèries
Resum
A theoretical study on the artemisinin decomposition mechanism is reported. The suggested pathways have been reproduced and the appearance of the final products can be explained in a satisfactory way. In addition, ... [+]
A theoretical study on the artemisinin decomposition mechanism is reported. The suggested pathways have been reproduced and the appearance of the final products can be explained in a satisfactory way. In addition, several intermediates and radicals have been found as relatively stable species, thus giving support to the current hypothesis that some of these species can be responsible for the antimalarial action of artemisinin and its derivatives. [-]
Drets d'accés
http://rightsstatements.org/vocab/CNE/1.0/
info:eu-repo/semantics/closedAccess
info:eu-repo/semantics/closedAccess
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