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Targeting Alzheimer's disease with multimodal polypeptide-based nanoconjugates
AAAS (American Association for the Advancement of Science) (2021-03-26)Alzheimer’s disease (AD), the most prevalent form of dementia, remains incurable mainly due to our failings in the search for effective pharmacological strategies. Here, we describe the development of targeted multimodal ... -
Temporal and Spatial Trends of Adverse Pregnancy and Birth Outcomes in a Sample of Births from a Public Hospital in Chile
Springer (2023-05-22)Understanding temporal and spatial trends in pregnancy and birth outcomes within an urban area is important for the monitoring of health indicators of a population. We conducted a retrospective cohort study of all births ... -
Técnica quirúrgica de la linfadenectomía inguinal videoendoscópica en el cáncer de vulva
Elsevier (2015)Introduction: Inguinal lymph node involvement is an important prognostic factor in patients with vulvar cancer. Inguinal lymph node dissection allows for staging and treatment of inguinal node disease but causes morbidity ... -
The Acoustic Dimension of Reading: Does Musical Aptitude Affect Silent Reading Fluency?
Frontiers Media (2020-04-29)Fluent reading in a foreign language includes a complex coordination process of visual and auditory nature as the reading brain transforms written symbols into speaking auditory patterns through subvocalization (inner ... -
The African striped mouse Lemniscomys barbarus as a model for aggression. Brain areas activated by agonistic encounters
Spanish Society of Anatomy (2017-01)During agonistic behavior several brain areas became differentially activated depending on the role the subject is taking. Several areas are mostly activated during the offender role and several others are activated if the ... -
The autistic brain: Exploring the strength of a different kind of mind
Hipatia Press (2015-02)Temple Grandin is one of the most well known persons with autism. Most people met her first when the neurologist Oliver Sacks portrayed her in his famous book “An anthropologist on Mars”. But Dr Grandin –BA in Psychology, ... -
The contribution of cooking appliances and residential traffic proximity to aerosol personal exposure
Tehran University of Medical Sciences (2021-01-22)Purpose Indoor and outdoor factors affect personal exposure to air pollutants. Type of cooking appliance (i.e. gas, electricity), and residential location related to traffic are such factors. This research aims to investigate ... -
The cost effectiveness of vacuum-assisted versus core-needle versus surgical biopsy of breast lesions
Elsevier (2017)Objectives To determine the cost effectiveness of breast biopsy by 9 G vacuum-assisted guided by vertical stereotaxy or ultrasonography in comparison with breast biopsy by 14 G core-needle biopsy and surgical biopsy. Material ... -
“The COVID-19 outbreak”—An empirical phenomenological study onperceptions and psychosocial considerations surrounding the immediateincorporation offinal-year Spanish nursing and medical students into the health system
Elsevier (2020)The COVID-19 pandemic has caused an unprecedented health crisis worldwide, with the numbers of infections and deaths worldwide multiplying alarmingly in a matter of weeks. Accordingly, governments have been forced to take ... -
The effect of abscisic acid chronic treatment on neuroinflammatory markers and memory in a rat model of high-fat diet induced neuroinflammation
BioMed Central (2016-10)Background Western diet and lifestyle are associated with overweight, obesity, and type 2 diabetes, which, in turn, are correlated with neuroinflammation processes. Exercise and a healthy diet are important in the ... -
The effect of age on the acquisition and selection of cancer driver mutations in sun-exposed normal skin
Elsevier (2021)Background: The accumulation of somatic mutations contributes to ageing and cancer. Sunlight is the principal aetiological factor associated with skin cancer development. However, genetic and phenotypic factors also ... -
The effect of calcium–magnesium mixtures in sol–gel coatings on bone tissue regeneration
Royal Society of Chemistry (2022)Calcium and magnesium are two elements essential for bone structure and metabolism. However, their synergistic or competitive effects on bone regeneration are often overlooked during biomaterial development. We examined ... -
The effect of long-term ultra-endurance exercise and SOD2 genotype on telomere shortening with age
American Physiological Society (2020-10-10)Telomere shortening, a well-known biomarker of aging, is a complex process influenced by several intrinsic and lifestyle factors. Although habitual exercise may promote telomere length maintenance, extreme endurance exercise ... -
The extent of aortic lymphadenectomy in locally advanced cervical cancer impacts on survival
Asian Society of Gynecologic Oncology (2021-01-06)Objective: The prognostic impact of surgical paraaortic staging remains unclear in patients with locally advanced cervical cancer (LACC). The objective of our study was to evaluate the results of the surgical technique ... -
The impact of patient support programs in Europe: a systematic literature review
Springer Nature (2022-06-21)Background and Objective : Patient support programs aim to provide solutions beyond the medication itself, by enhancing treatment adherence, improving clinical outcomes, elevating patient experience, and/or increasing ... -
The Interplay between Natural Selection and Susceptibility to Melanoma on Allele 374F of SLC45A2 Gene in a South European Population
Public Library of Science (2014)We aimed to study the selective pressures interacting on SLC45A2 to investigate the interplay between selection and susceptibility to disease. Thus, we enrolled 500 volunteers from a geographically limited population ... -
The JAK2 pathway is activated in idiopathic pulmonary fibrosis
BioMed Central (2018)Background: Idiopathic pulmonary fibrosis (IPF) is the most rapidly progressive and fatal fibrotic disorder, with no curative therapies. The signal transducer and activator of transcription 3 (STAT3) protein is activated ... -
The maternal hormone in the male brain: Sexually dimorphic distribution of prolactin signalling in the mouse brain
Public Library of Science (2018)Research of the central actions of prolactin is highly focused on females, but this hormone has also documented roles in male physiology and behaviour. Here, we provide the first description of the pattern of prolactin-derived ...