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Metabolism of N-ethylhexedrone and buphedrone: An in vivo study in mice using HPLC-MS/MS
(Elsevier, 2020-08-25)
N-ethylhexedrone (NEH) and buphedrone (BUPH) are synthetic drugs structurally related to natural cathinone. These synthetic cathinones (SC) are members of the heterogenous family of new psychoactive substances (NPS), which ...
Dietary pesticide chlorpyrifos-methyl affects arachidonic acid metabolism including phospholipid remodeling in Atlantic salmon (Salmo salar L.)
(Elsevier, 2018-02-01)
The pesticide chlorpyrifos-methyl (CLP-m) has been identified in plant ingredients intended for aquaculture feed production. To investigate systemic effects of CLP-m with emphasis on lipid metabolism, post-smolt Atlantic ...
Global Assessment of Seawater Intrusion Problems (Status and Vulnerability)
(Springer Netherlands, 2018)
In this research paper we propose a novel method to perform an integrated analysis of the status and vulnerability of coastal aquifers to seawater intrusion (SWI). The method is based on a conceptual approach of intrusion ...
Comparison of phosphodiesterase type V inhibitors use in eight European cities through analysis of urban wastewater
(Elsevier, 2018-06)
In this work a step forward in investigating the use of prescription drugs, namely erectile dysfunction products, at European level was taken by applying the wastewater-based epidemiology approach. 24-h composite samples ...
Using electrical resistivity tomography to assess the effectiveness of managed aquifer recharge in a salinized coastal aquifer
(Springer, 2018-02)
Over 40 years, the detrital aquifer of the Plana de Castellón (Spanish Mediterranean coast) has been subjected to seawater intrusion because of long dry periods combined with intensive groundwater exploitation. Against ...
Identification of new, very long-chain polyunsaturated fatty acids in fish by gas chromatography coupled to quadrupole/time-of-flight mass spectrometry with atmospheric pressure chemical ionization
(Springer, 2021-2)
The characterization of very long-chain (>C24) polyunsaturated fatty acids (VLC-PUFAs), which are essential in the vision, neural function, and reproduction of vertebrates, is challenging because of the lack of reference ...
Isotope Dilution LC-ESI-MS/MS and low resolution Selected Reaction Monitoring as a tool for the accurate quantification of urinary testosterone
(Elsevier, 2018-09)
A new analytical method for the quantification of testosterone in human urine samples by isotope dilution mass spectrometry is proposed. A standard solution of 13C2-testosterone is added to the samples at the beginning of ...
A Refined Nontarget Workflow for the Investigation of Metabolites through the Prioritization by in Silico Prediction Tools
(American Chemical Society, 2019-04-11)
The application of nontargeted strategies based on high-resolution mass spectrometry (HRMS) directed toward the discovery of metabolites of known contaminants in fish is an interesting alternative to true nontarget screening. ...
Comprehensive investigation on synthetic cannabinoids: metabolic behaviour, detectability and potency testing, using 5F-APP-PICA and AMBFUBINACA as model compounds.
(Wiley, 2019-09)
Synthetic cannabinoids (SCs) represented 45% of new psychoactive substances seizures in Europe (data from 2016). The consumption of SCs is an issue of concern due to their still unknown toxicity and effects on human health, ...
Do background levels of the pesticide pirimiphosmethyl in plant-based aquafeeds affect food safety of farmed Atlantic salmon?
(Taylor & Francis Group, 2020-10-20)
The substitution of fish oil and fishmeal with plant-based ingredients in commercial aquafeeds for Atlantic salmon, may introduce novel contaminants that have not previously been associated with farmed fish. The organophosphate ...