Non-target screening and human risk assessment for adult and child populations of semi-volatile organic compounds in residential indoor dust in Spain
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Otros documentos de la autoría: Fuentes-Ferragud, Esther; Miralles, Pablo; López, Antonio; Ibañez Martinez, Maria; Coscolla, Clara
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Título
Non-target screening and human risk assessment for adult and child populations of semi-volatile organic compounds in residential indoor dust in SpainAutoría
Fecha de publicación
2023-08-18Editor
ElsevierCita bibliográfica
FUENTES-FERRAGUD, Esther, et al. Non-target screening and human risk assessment for adult and child populations of semi-volatile organic compounds in residential indoor dust in Spain. Chemosphere, 2023, vol. 340, p. 139879.Tipo de documento
info:eu-repo/semantics/articleVersión
info:eu-repo/semantics/submittedVersionPalabras clave / Materias
Resumen
In this work, an analytical strategy based on non-target screening of semi-volatile organic compounds and subsequent risk assessment for adult and child populations has been conducted for the first time in household ... [+]
In this work, an analytical strategy based on non-target screening of semi-volatile organic compounds and subsequent risk assessment for adult and child populations has been conducted for the first time in household indoor dust samples in Spain. The methodology was based on a microwave-assisted extraction followed by gas chromatography coupled to high resolution mass spectrometry determination, using a hybrid quadrupole-orbitrap analyzer. The procedure was applied to 19 residential indoor dust samples, collected in different Spanish regions (namely Galicia, La Rioja, Catalunya, the Balearic Islands, and the Valencian Region). From the generated data, 4067 features were obtained, of which 474 compounds were tentatively identified with a high level of identification confidence (probable structure by library spectrum match or confirmed by reference standard), using a restrictive set of identification criteria. Most of the identified chemicals were natural products, metabolites, additives, and substances with industrial applications in the field of foods, cosmetics, pharmaceuticals, pesticides, and plastics. Finally, risk assessment was carried out by applying the threshold of toxicological concern approach, showing that risk to adult and child populations associated with the presence of the identified substances in the indoor dust was not expected, although the existence of indoor environments with conditions of potential risk cannot be discarded under a worst-case scenario approach. [-]
Entidad financiadora
European Regional Development Funds (ERDF) Operational Programme of the Valencian Region (2014–2020) | Institute of Health Carlos III (ISCiii) | European Union-Next Generation EU
Código del proyecto o subvención
CD22/00070
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© 2023 Elsevier Ltd. All rights reserved.
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http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/openAccess
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