An easy and green assay to determine albendazole and ivermectin in veterinary preparations by micellar liquid chromatography
![Thumbnail](/xmlui/bitstream/handle/10234/202906/85408.pdf.jpg?sequence=4&isAllowed=y)
Visualitza/
Impacte
![Google Scholar](/xmlui/themes/Mirage2/images/uji/logo_google.png)
![Microsoft Academico](/xmlui/themes/Mirage2/images/uji/logo_microsoft.png)
Metadades
Mostra el registre complet de l'elementcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7013
comunitat-uji-handle3:10234/8638
comunitat-uji-handle4:
INVESTIGACIONMetadades
Títol
An easy and green assay to determine albendazole and ivermectin in veterinary preparations by micellar liquid chromatographyAutoria
Data de publicació
2023-01-25Editor
WileyCita bibliogràfica
PAWAR, Rajendra‐Prasad, et al. An easy and green assay to determine albendazole and ivermectin in veterinary preparations by micellar liquid chromatography. Electrophoresis, 2024, 45, 3-4, p. 2212-217Tipus de document
info:eu-repo/semantics/articleVersió
info:eu-repo/semantics/publishedVersionParaules clau / Matèries
Resum
A procedure to determine albendazole and ivermectin in veterinary formulations, like tablet, bolus, oral suspensions, and injections by micellar liquid chromatography, has been developed. Sample preparation was a batch ... [+]
A procedure to determine albendazole and ivermectin in veterinary formulations, like tablet, bolus, oral suspensions, and injections by micellar liquid chromatography, has been developed. Sample preparation was a batch solid-to-liquid extraction in mobile phase, consisting of a stirring step (15 min), followed by ultrasonication (15 min) and filtration of the obtained supernatant, to reach a target concentration of 2 mg/L for both analytes. Using a mobile phase of 0.15 M sodium dodecyl sulfate—6% 1-pentanol buffered at pH 3 with a 0.01 M phosphate salt, running at 1 mL/min through a C18 column, both drugs were resolved in less than 10 min. Absorbance detection wavelength was 292 nm. Procedure was validated by the guidelines of the International Council on Harmonization in terms of specificity, calibration range (0.025–5 mg/L), trueness (97.8%–102.6%), precision (<2.2%), and system suitability. The method was found easy-to-handle, low cost, safe, green, and with high sample-throughput, thus useful for routine analysis. Therefore, it represents a valuable alternative for quality control of veterinary formulations. It was applied to samples of veterinary formulations purchased from local chemists and veterinarians, and label claims were inside the acceptance criteria (95%–105%). [-]
Publicat a
Electrophoresis, 2024, 45, 3-4Entitat finançadora
Ministerio de Ciencia, Innovación y Universidades (Spain) | Ministry of Science and Technology, Government of India | MCIN/AEI/10.13039/501100011033 | Projekt DEAL
Codi del projecte o subvenció
PID2019-106708GB-I00 | Sl.No.64
Títol del projecte o subvenció
Open Access funding
Drets d'accés
© 2023 The Authors. Electrophoresis published by Wiley-VCH GmbH.
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Apareix a les col.leccions
- QFA_Articles [825]