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Prevalence of Hyperuricemia and Its Association with Cardiovascular Risk Factors and Subclinical Target Organ Damage
dc.contributor.author | Antelo Pais, Paula | |
dc.contributor.author | PRIETO-DIAZ, MIGUEL ANGEL | |
dc.contributor.author | MICÓ PÉREZ, RAFAEL MANUEL | |
dc.contributor.author | Pallarés-Carratalá, Vicente | |
dc.contributor.author | Velilla-zancada, Sonsoles | |
dc.contributor.author | Polo García, José Luis | |
dc.contributor.author | barquilla garcía, alfonso | |
dc.contributor.author | Ginel-Mendoza, Leovigildo | |
dc.contributor.author | Segura Fragoso, Antonio | |
dc.contributor.author | Vitelli-Storelli, Facundo | |
dc.contributor.author | Martin, V. | |
dc.contributor.author | Hermida-Ameijeiras, Alvaro | |
dc.contributor.author | Cinza-Sanjurjo, Sergio | |
dc.date.accessioned | 2023-01-17T08:21:10Z | |
dc.date.available | 2023-01-17T08:21:10Z | |
dc.date.issued | 2022-12-21 | |
dc.identifier.citation | Antelo-Pais, P.; Prieto-Díaz, M.Á.; Micó-Pérez, R.M.; PallarésCarratalá, V.; Velilla-Zancada, S.; Polo-García, J.; Barquilla-García, A.; Ginel-Mendoza, L.; Segura-Fragoso, A.; Vitelli-Storelli, F.; et al. Prevalence of Hyperuricemia and Its Association with Cardiovascular Risk Factors and Subclinical Target Organ Damage. J. Clin. Med. 2023, 12, 50. https:// doi.org/10.3390/jcm12010050 | ca_CA |
dc.identifier.issn | 2077-0383 | |
dc.identifier.uri | http://hdl.handle.net/10234/201369 | |
dc.description.abstract | The role of uric acid levels in the cardiovascular continuum is not clear. Our objective is to analyze the prevalence of hyperuricemia (HU) and its association with cardiovascular risk factors (CVRF), subclinical target organ damage (sTOD), and cardiovascular diseases (CVD). We evaluated the prevalence of HU in 6.927 patients included in the baseline visit of the IBERICAN study. HU was defined as uric acid levels above 6 mg/dL in women, and 7 mg/dL in men. Using adjusted logistic regression models, the odds ratios were estimated according to CVRF, sTOD, and CVD. The prevalence of HU was 16.3%. The risk of HU was higher in patients with pathological glomerular filtration rate (aOR: 2.92), heart failure (HF) (aOR: 1.91), abdominal obesity (aOR: 1.80), hypertension (HTN) (aOR: 1.65), use of thiazides (aOR: 1.54), left ventricular hypertrophy (LVH) (aOR: 1.36), atrial fibrillation (AFIB) (aOR: 1.29), and albuminuria (aOR: 1.27). On the other hand, being female (aOR: 0.82) showed a reduced risk. The prevalence of HU was higher in men, in patients presenting CVRF such as HTN and abdominal obesity, and with co-existence of LVH, atrial fibrillation (AFIB), HF, and any form of kidney injury. These associations raise the possibility that HU forms part of the early stages of the cardiovascular continuum. This may influence its management in Primary Healthcare because the presence of HU could mean an increased CV risk in the patients. | ca_CA |
dc.format.extent | 13 p. | ca_CA |
dc.format.mimetype | application/pdf | ca_CA |
dc.language.iso | eng | ca_CA |
dc.publisher | MDPI | ca_CA |
dc.relation.isPartOf | J. Clin. Med. 2023, 12, 50. https://doi.org/10.3390/jcm12010050 | ca_CA |
dc.rights | Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). | ca_CA |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | ca_CA |
dc.subject | hyperuricemia | ca_CA |
dc.subject | cardiovascular risk | ca_CA |
dc.subject | prevalence | ca_CA |
dc.subject | associated risk | ca_CA |
dc.title | Prevalence of Hyperuricemia and Its Association with Cardiovascular Risk Factors and Subclinical Target Organ Damage | ca_CA |
dc.type | info:eu-repo/semantics/article | ca_CA |
dc.identifier.doi | https:// doi.org/10.3390/jcm12010050 | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | ca_CA |
dc.type.version | info:eu-repo/semantics/publishedVersion | ca_CA |
project.funder.name | SEMERGEN Foundation | ca_CA |
dc.subject.ods | 3. Salud y bienestar |
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