Biomaterials for Neural Tissue Engineering
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Show full item recordcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/36080
comunitat-uji-handle3:10234/36082
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INVESTIGACIONMetadata
Title
Biomaterials for Neural Tissue EngineeringDate
2021Publisher
Frontiers MediaISSN
2673-3013Bibliographic citation
Doblado LR, Martínez-Ramos C and Pradas MM (2021) Biomaterials for Neural Tissue Engineering. Front. Nanotechnol. 3:643507. doi: 10.3389/fnano.2021.643507Type
info:eu-repo/semantics/articleVersion
info:eu-repo/semantics/publishedVersionSubject
Abstract
The therapy of neural nerve injuries that involve the disruption of axonal pathways or
axonal tracts has taken a new dimension with the development of tissue engineering
techniques. When peripheral nerve injury ... [+]
The therapy of neural nerve injuries that involve the disruption of axonal pathways or
axonal tracts has taken a new dimension with the development of tissue engineering
techniques. When peripheral nerve injury (PNI), spinal cord injury (SCI), traumatic brain
injury (TBI), or neurodegenerative disease occur, the intricate architecture undergoes
alterations leading to growth inhibition and loss of guidance through large distance.
To improve the limitations of purely cell-based therapies, the neural tissue engineering
philosophy has emerged. Efforts are being made to produce an ideal scaffold based on
synthetic and natural polymers that match the exact biological and mechanical properties
of the tissue. Furthermore, through combining several components (biomaterials, cells,
molecules), axonal regrowth is facilitated to obtain a functional recovery of the neural
nerve diseases. The main objective of this review is to investigate the recent approaches
and applications of neural tissue engineering approaches. [-]
Is part of
Frontiers in Nanotechnology 3:643507Funder Name
MINECO | Spanish Ministry of Education, Culture and Sports
Project code
AEI RTI2018-095872-B-C21 | C22/ERDF | FPU15/04975
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info:eu-repo/semantics/openAccess
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- MED_Articles [657]