Effects of probiotics on cognitive and emotional functions in healthy older adults: Protocol for a double-blind randomized placebo-controlled crossover trial
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Altres documents de l'autoria: Ruiz González, Cristofer; Cardona Mena, Diana María; Rodriguez-Arrastia, Miguel; Ropero-Padilla, Carmen; Rueda-Ruzafa, Lola; Carvajal, Maria Francisca; Sánchez Labraca, María Nuria; Aparicio-Mota, Adrián; Roman, Pablo
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Títol
Effects of probiotics on cognitive and emotional functions in healthy older adults: Protocol for a double-blind randomized placebo-controlled crossover trialAutoria
Data de publicació
2022-01-25Editor
WileyCita bibliogràfica
Ruiz‐Gonzalez, C., Cardona, D., Rodriguez‐Arrastia, M., Ropero‐Padilla, C., Rueda‐Ruzafa, L., Carvajal, F., Sanchez‐Labraca, N., Aparicio, Mota A., & Roman, P. (2022). Effects of probiotics on cognitive and emotionalfunctions in healthy older adults: Protocol for a double‐blindrandomized placebo‐controlled crossover trial. Research in Nursing & Health,1–13. https://doi.org/10.1002/nur.22209RUIZ‐GONZALEZET AL.|13Tipus de document
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Resum
Aging is a process that includes changes in cognitive and emotional functions,as well as changes in the diversity and integrity of gut microbiota. Probiotictreatments have recently been studied as a potential new ... [+]
Aging is a process that includes changes in cognitive and emotional functions,as well as changes in the diversity and integrity of gut microbiota. Probiotictreatments have recently been studied as a potential new therapeutic approachto alleviate a wide range of problems in other populations; however, clinicalstudies in older adults remain insufficient and limited. Thus, the aim of thisproject is to evaluate the efficacy of a multispecies probiotic formulation as atherapeutic strategy for attenuating the emotional and cognitive decline asso-ciated with aging in adults over the age of 55. This is a double‐blind randomizedplacebo‐controlled crossover trial involving at least 32 older adults andcomparing two conditions: (a) probiotic, providing a multispecies probiotic for10 weeks (Lactobacillus rhamnosusandBifidobacterium lactis); and (b) placebo,receiving a harmless substance (potato starch). Despite the increasing use ofprobiotics for the treatment of cognitive and emotional problems, no study hasyet focused on this group, to the best of our knowledge. Therapeutic strategiesof the kind outlined in this protocol will help to shed light on the current state ofknowledge about this topic, as well as promote health programs tailored to thispopulation, which would encourage active aging and healthy lifestyles. Not onlydo we expect improvements in the emotional dimension in terms of anxiety,stress, depression, and sleep quality, we also expect improvements in the cog-nitive dimension in terms of attention,memory, and decreased impulsivity. [-]
Publicat a
Res Nurs Health., 2022Entitat finançadora
Health Research Center CEINSA | University of Almeria, Spain
Codi del projecte o subvenció
001403
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© 2022 Wiley Periodicals LLC
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