Investigation of Drugs in Wastewater: Removal Efficiency in a Treatment Plant and Environmental Impact Assessment
Ver/ Abrir
Metadatos
Mostrar el registro completo del ítemcomunitat-uji-handle:10234/158176
comunitat-uji-handle2:10234/71324
comunitat-uji-handle3:10234/98504
comunitat-uji-handle4:
TFG-TFMMetadatos
Título
Investigation of Drugs in Wastewater: Removal Efficiency in a Treatment Plant and Environmental Impact AssessmentAutoría
Tutor/Supervisor; Universidad.Departamento
Hernández Hernández, Félix Javier; Sancho Llopis, Juan Vicente; Universitat Jaume I. Departament de Química Física i AnalíticaFecha de publicación
2020-07-24Editor
Universitat Jaume IResumen
This study assessed the presence of 41 pharmaceuticalsin wastewater samples from the
north of Spain. The samples under study were collected during a week, before the treatment
(influent) and after treatment (effluent) ... [+]
This study assessed the presence of 41 pharmaceuticalsin wastewater samples from the
north of Spain. The samples under study were collected during a week, before the treatment
(influent) and after treatment (effluent) in a wastewater treatment plant (WWTP). Additionally,
samples reaching the inlet of the WWTP from hospital discharge were also collected. The
wastewater samples were analysed by ultra-high performance liquid chromatography coupled
to tandem mass spectrometry using triple quadrupole analyzer (UHPLC-MS/MS QqQ) due to its
greatselectivity and sensitivity. Analyses were performed by direct injection (DI) of the samples;
so, pre-concentration treatments were avoided. Moreover, in order to correct matrix effects,
Isotopically-Labelled Internal Standards (ILIS) available for some pharmaceuticals were added to
the samples. Acetaminophen and Gabapentin were the most frequently detected compounds in
both influent wastewater (IWW) and Hospital discharge. In EWW, it was observed a decrease in
the concentrations of pharmaceuticals in comparison to the influent samples. The removal
efficiency (RE) (%) was calculated by comparing the mass load of the influent and the effluent
samples. From the 30 compounds detected in wastewater, only three pharmaceuticals
(Acetaminophen, Atorvastatin and Enalapril) presented a 100% RE, which means that they were
completely eliminated after passing through the WWTP. The results of this work indicate that
most of pharmaceuticals under study are present in treated wastewater, and consequently they
reach the aquatic environment. Hazard quotients (HQ) were calculated to assess the potential
environmental risks of these pharmaceuticals. The results showed that generally there are not
significant risks associated to the presence of pharmaceuticals in the aquatic environment
although Ciprofloxacin, Diclofenac, Norfloxacin and Venlafaxine presented an HQ > 1 implying
that the amount of these compounds released into the environment is above the non-effect
concentration. The results from this study contribute to the better understanding of potential
risks associated to the presence of pharmaceuticals in urban wastewater and their impact on
the aquatic environment. [-]
Palabras clave / Materias
Descripción
Treball Final de Grau en Química. Codi: QU0943. Curs acadèmic: 2019/2020
Tipo de documento
info:eu-repo/semantics/bachelorThesisDerechos de acceso
info:eu-repo/semantics/openAccess
Aparece en las colecciones
- Grau en Química [265]