The mediating role of adiposity in the longitudinal association between cardiorespiratory fitness and blood pressure in adolescents: LabMed cohort study
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Otros documentos de la autoría: Beltran Valls, Maria Reyes; Santos, Rute; Mota, Jorge; Moreira, Carla; Lopes, Luís; Agostinis-Sobrinho, César
Metadatos
Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/174799
comunitat-uji-handle3:10234/174800
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INVESTIGACIONMetadatos
Título
The mediating role of adiposity in the longitudinal association between cardiorespiratory fitness and blood pressure in adolescents: LabMed cohort studyAutoría
Fecha de publicación
2020-10-12Editor
WileyISSN
0014-2972Cita bibliográfica
Beltran‐Valls, MR, Santos, R, Mota, J, Moreira, C, Lopes, L, Agostinis‐Sobrinho, C. The mediating role of adiposity in the longitudinal association between cardiorespiratory fitness and blood pressure in adolescents: LabMed cohort study. Eur J Clin Invest. 2020; 00:e13430. https://doi.org/10.1111/eci.13430Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
https://onlinelibrary.wiley.com/doi/full/10.1111/eci.13430Versión
info:eu-repo/semantics/acceptedVersionPalabras clave / Materias
Resumen
Background
The aim of this prospective cohort study was to examine whether the association between the cardiorespiratory fitness (CRF) at baseline and blood pressure (BP) at follow‐up is mediated by adiposity in ... [+]
Background
The aim of this prospective cohort study was to examine whether the association between the cardiorespiratory fitness (CRF) at baseline and blood pressure (BP) at follow‐up is mediated by adiposity in adolescents.
Materials and methods
The sample comprised 734 adolescents (349 girls) aged 12‐18 years from the LabMed Physical Activity Cohort Study. The variables of interest were measured in 2011 (baseline) and in 2013 (2‐year follow‐up). CRF was assessed by the 20‐m shuttle run test. Body mass index, waist circumference, body fat percentage, pubertal status and resting BP were assessed according to standard procedures. Boot‐strapped mediation procedures were performed, and indirect effects (IE) with confidence intervals (CI) not including zero were considered statistically significant.
Results
After adjusting for potential confounders, body mass index acted as a mediator of the relationship between CRF and systolic BP (IE = −0. 023; CI = −0.039; −0.009), pulse pressure (IE = −0.023; CI = −0.034; −0.012) and rate product pressure (IE = −2.839; CI = −5.329; −0.340). Similar results were obtained for waist circumference as mediator for systolic BP (IE = −0.019; CI = −0.033; −0.005), pulse pressure (IE = −0.017; CI = −0.028; −0.007) and rate product pressure (IE = −3.793; CI = −6.097; −1.689). Likewise, body fat percentage mediated the association for: systolic BP (IE = −0.029; CI = −0.048; −0.010), pulse pressure (IE = −0.027; CI = −0.041; −0.013) and rate product pressure (IE = −4.280; CI = −7.488; −1.264).
Conclusions
Adiposity mediated the association between CRF and BP in adolescents. Therefore, both optimal CRF and adiposity levels are important to maintain normal BP ranges throughout adolescence. [-]
Publicado en
Eur J Clin Invest. 2020; 00:e13430Proyecto de investigación
Portuguese Foundation for Science and Technology. Grant Numbers: CEECIND/ 01069/2017, EECIND/01089/2017, FCT/UIDB/00617/2020, SFRH/ BSAB/142983/2018, UID/DTP/00617/2019. Spanish Ministry of Science, Innovation and Universities. Grant Number: CAS19/00032Derechos de acceso
© 2020 Stichting European Society for Clinical Investigation Journal Foundation. Published by John Wiley & Sons Ltd
http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/openAccess
http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/openAccess
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