Effects of bilingualism on white matter atrophy in mild cognitive impairment: a diffusion tensor imaging study
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Show full item recordcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/8033
comunitat-uji-handle3:10234/8636
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INVESTIGACIONMetadata
Title
Effects of bilingualism on white matter atrophy in mild cognitive impairment: a diffusion tensor imaging studyAuthor (s)
Date
2019-12-05Publisher
WileyBibliographic citation
MARÍN MARÍN, Lidón; COSTUMERO, Víctor; BELLOCH, Vicente; ESCUDERO, Joaquín; BAQUERO TOLEDO, Miguel; PARCET, María Antonia; ÁVILA, César (2019). Effects of bilingualism on white matter atrophy in mild cognitive impairment: a diffusion tensor imaging study. European Journal of Neurology, online 5/12/2019Type
info:eu-repo/semantics/articlePublisher version
https://onlinelibrary.wiley.com/doi/full/10.1111/ene.14135Version
info:eu-repo/semantics/publishedVersionAbstract
Background and purpose:Previous investigations show that bilinguals exhibitthe first symptoms of dementia 4–5 years later than monolinguals. Therefore,bilingualism has been proposed as a cognitive reserve mechanism. ... [+]
Background and purpose:Previous investigations show that bilinguals exhibitthe first symptoms of dementia 4–5 years later than monolinguals. Therefore,bilingualism has been proposed as a cognitive reserve mechanism. Recent stud-ies have advanced towards an understanding of the brain mechanisms underly-ing bilingualism’s protection against dementia, but none of them deals withwhite matter (WM) diffusion.Methods:In this study, the topic was investigated by measuring WM integrityin a sample of 35 bilinguals and 53 passive bilinguals with mild cognitiveimpairment.Results:No significant differences were found between the groups in cognitivelevel, education, age or sex. However, bilinguals showed higher mean diffusiv-ity in the fornix, but higher fractional anisotropy, lower mean diffusivity, axialdiffusivity and radial diffusivity in the parahippocampal cingulum, and lowerradial diffusivity in the right uncinate fasciculus. Significant correlations werealso found between WM integrity in the left parahippocampal cingulum andthe Boston Naming Test in passive bilinguals.Conclusions:These results suggest that bilingualism contributes to a differen-tial pattern of WM disintegration due to mild cognitive impairment in fibersrelated to bilingualism and memory. [-]
Investigation project
1) Spanish Ministry of Education. Grant Number: FPU17/00698; 2) Spanish Ministry of Economy, Industry and Competitiveness. Grant Number: IJCI‐2016‐29247; 3) Fundació Marató TV3. Grant Number: 201410‐30‐31Rights
http://rightsstatements.org/vocab/CNE/1.0/
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
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