Distinct branches of the N-end rule pathway modulate the plantimmune response
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comunitat-uji-handle2:10234/2508
comunitat-uji-handle3:10234/6999
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Title
Distinct branches of the N-end rule pathway modulate the plantimmune responseAuthor (s)
Date
2019Publisher
WileyISSN
0028-646X; 1469-8137Bibliographic citation
VICENTE, Jorge, et al. Distinct branches of the N‐end rule pathway modulate the plant immune response. New Phytologist, 2019, vol. 221, no 2, p. 988-1000.Type
info:eu-repo/semantics/articlePublisher version
https://nph.onlinelibrary.wiley.com/doi/full/10.1111/nph.15387Version
info:eu-repo/semantics/publishedVersionSubject
Abstract
The N‐end rule pathway is a highly conserved constituent of the ubiquitin proteasome system, yet little is known about its biological roles.
Here we explored the role of the N‐end rule pathway in the plant immune ... [+]
The N‐end rule pathway is a highly conserved constituent of the ubiquitin proteasome system, yet little is known about its biological roles.
Here we explored the role of the N‐end rule pathway in the plant immune response. We investigated the genetic influences of components of the pathway and known protein substrates on physiological, biochemical and metabolic responses to pathogen infection.
We show that the glutamine (Gln) deamidation and cysteine (Cys) oxidation branches are both components of the plant immune system, through the E3 ligase PROTEOLYSIS (PRT)6. In Arabidopsis thaliana Gln‐specific amino‐terminal (Nt)‐amidase (NTAQ1) controls the expression of specific defence‐response genes, activates the synthesis pathway for the phytoalexin camalexin and influences basal resistance to the hemibiotroph pathogen Pseudomonas syringae pv tomato (Pst). The Nt‐Cys ETHYLENE RESPONSE FACTOR VII transcription factor substrates enhance pathogen‐induced stomatal closure. Transgenic barley with reduced HvPRT6 expression showed enhanced resistance to Ps. japonica and Blumeria graminis f. sp. hordei, indicating a conserved role of the pathway.
We propose that that separate branches of the N‐end rule pathway act as distinct components of the plant immune response in flowering plants. [-]
Is part of
New Phytologist (2019) 221.Investigation project
BB/K000144/1 ; BB/M029441/1 ; BB/K000063/1 ; GRK1026 ; BIO2015-68130 ; I1464-B16 ; PI-1B2015-33Rights
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Except where otherwise noted, this item's license is described as © 2018 The Authors New Phytologist © 2018 New Phytologist Trust. This is an open access article under the terms of the Creative Commons Attribution License, which permits use,distribution and reproduction in any medium, provided the original work is properly cited.