Is There A Role for Abscisic Acid, A Proven Anti-Inflammatory Agent, in the Treatment of Ischemic Retinopathies?
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Altres documents de l'autoria: Baliño, Pablo; Gomez-Cadenas, Aurelio; López Malo, Daniel; Romero, Francisco J.; Muriach, Maria
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Mostra el registre complet de l'elementcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/2508
comunitat-uji-handle3:10234/6999
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INVESTIGACIONMetadades
Títol
Is There A Role for Abscisic Acid, A Proven Anti-Inflammatory Agent, in the Treatment of Ischemic Retinopathies?Autoria
Data de publicació
2019Editor
MDPIISSN
2076-3921Cita bibliogràfica
BALIÑO, Pablo, et al. Is There A Role for Abscisic Acid, A Proven Anti-Inflammatory Agent, in the Treatment of Ischemic Retinopathies?. Antioxidants, 2019, vol. 8, no 4, p. 104Tipus de document
info:eu-repo/semantics/articleVersió de l'editorial
https://www.mdpi.com/2076-3921/8/4/104Versió
info:eu-repo/semantics/publishedVersionParaules clau / Matèries
Resum
Ischemic retinopathies (IRs) are the main cause of severe visual impairment and sight loss, and are characterized by loss of blood vessels, accompanied by hypoxia, and neovascularization. Actual therapies, based on ... [+]
Ischemic retinopathies (IRs) are the main cause of severe visual impairment and sight loss, and are characterized by loss of blood vessels, accompanied by hypoxia, and neovascularization. Actual therapies, based on anti-vascular endothelial growth factor (VEGF) strategies, antioxidants or anti-inflammatory therapies are only partially effective or show some adverse side effects. Abscisic acid (ABA) is a phytohormone present in vegetables and fruits that can be naturally supplied by the dietary intake and has been previously studied for its benefits to human health. It has been demonstrated that ABA plays a key role in glucose metabolism, inflammation, memory and tumor growth. This review focuses on a novel and promising role of ABA as a potential modulator of angiogenesis, oxidative status and inflammatory processes in the retina, which are the most predominant characteristics of the IRs. Thus, this nutraceutical compound might shed some light in new therapeutic strategies focused in the prevention or amelioration of IRs-derived pathologies. [-]
Publicat a
Antioxidants, 2019, vol. 8, no 4Proyecto de investigación
Generalitat Valenciana: Prometeo 94/2016; Universitat Jaume I: UJI-A2016-03Drets d'accés
info:eu-repo/semantics/openAccess
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