β-Lactam Antibiotics Modify Root Architecture and Indole Glucosinolate Metabolism in Arabidopsis thaliana
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Other documents of the author: Gudiño, Marco; Blanco-Touriñán, Noel; Arbona, Vicent; Gomez-Cadenas, Aurelio; Blazquez, Miguel; Navarro-García, Federico
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https://doi.org/10.1093/pcp/pcy128 |
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Title
β-Lactam Antibiotics Modify Root Architecture and Indole Glucosinolate Metabolism in Arabidopsis thalianaAuthor (s)
Date
2018Publisher
Oxford University PressISSN
0032-0781; 1471-9053)Bibliographic citation
Marco E Gudiño, Noel Blanco-Touriñán, Vicent Arbona, Aurelio Gómez-Cadenas, Miguel A Blázquez, Federico Navarro-García; β-Lactam Antibiotics Modify Root Architecture and Indole Glucosinolate Metabolism in Arabidopsis thaliana, Plant and Cell Physiology, Volume 59, Issue 10, 1 October 2018, Pages 2086–2098, https://doi.org/10.1093/pcp/pcy128Type
info:eu-repo/semantics/articlePublisher version
https://academic.oup.com/pcp/article/59/10/2086/5050038?searchresult=1Version
info:eu-repo/semantics/publishedVersionSubject
Abstract
The presence of antibiotics in soils could be due to natural
production by soil microorganisms or to the effect of anthropogenic activities. However, the impact of these compounds on plant physiology has not been ... [+]
The presence of antibiotics in soils could be due to natural
production by soil microorganisms or to the effect of anthropogenic activities. However, the impact of these compounds on plant physiology has not been thoroughly
investigated. To evaluate the effect of b-lactam antibiotics
(carbenicillin and penicillin) on the growth and development of Arabidopsis thaliana roots, plants were grown in
the presence of different amounts and we found a reduction
in root size, an increase in the size of root hairs as well as an
abnormal position closer to the tip of the roots. Those phenomena were dependent on the accumulation of both antibiotics inside root tissues and also correlated with a decrease
in size of the root apical meristem not related to an alteration in cell division but to a decrease in cell expansion.
Using an RNA sequencing analysis, we detected an increase
in the expression of genes related to the response to oxidative stress, which would explain the increase in the levels of
endogenous reactive oxygen species found in the presence of
those antibiotics. Moreover, some auxin-responsive genes
were misregulated, especially an induction of CYP79B3, possibly explaining the increase in auxin levels in the presence of
carbenicillin and the decrease in the amount of indole glucosinolates, involved in the control of fungal infections.
Accordingly, penicillin-treated plants were hypersensitive
to the endophyte fungus Colletotrichum tofieldiae. These results underscore the risks for plant growth of b-lactam antibiotics in agricultural soils, and suggest a possible function
for these compounds as fungus-produced signaling molecules to modify plant behavior. [-]
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Plant Cell Physiol. 59(10): 2086–2098 (2018)Rights
© The Author(s) 2018. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists.
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