Additives for reducing the toxicity of respirable crystalline silica. SILIFE project
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Title
Additives for reducing the toxicity of respirable crystalline silica. SILIFE projectAuthor (s)
Date
2017-10-23Publisher
EDP SciencesBibliographic citation
MONFORT GIMENO, Eliseo; LÓPEZ LILAO, Ana; ESCRIG, Alberto; IBÁÑEZ, María Jesús; BONVICINI, Giuliana; CREUTZENBERG, O.; ZIEMANN, Christina. (2017). Additives for reducing the toxicity of respirable crystalline silica. SILIFE project. E3S Web of Conferences, v. 19, International Conference Energy, Environment and Material Systems (EEMS 2017)Type
info:eu-repo/semantics/conferenceObjectPublisher version
https://www.e3s-conferences.org/articles/e3sconf/abs/2017/07/e3sconf_eems2017_02 ...Version
info:eu-repo/semantics/publishedVersionSubject
Abstract
Prolonged inhalation of crystalline silica particles has long been known to cause lung
inflammation and development of the granulomatous and
a fibrogenic lung disease
known as silicosis
. The ... [+]
Prolonged inhalation of crystalline silica particles has long been known to cause lung
inflammation and development of the granulomatous and
a fibrogenic lung disease
known as silicosis
. The
International Agency for Research on Cancer (IARC) has classified Respirable Crystalline Silica (RCS) in
the form of quartz and cristobalite from occupational sources as carcinogenic for
humans (category 1)
. In
this regard, numerous studies suggest t
hat the toxicity of quartz is conditioned by the surface chemistry of
the quartz particles and
by
the
density and abundance of silanol groups.
Blocking these groups to avoid their
interaction with cellular membranes would theoretically be possible in order
to reduce or even to eliminate
the toxic effect
. In this regard, t
he
main contribution of the presented research is the development of
detoxifying processes based on coating technologies at industrial scale, since the previous studies reported
on literatu
re were carried out at lab scale. The
results
obtained in two European projects show
ed that
the wet
method to obtain quartz surface coatings
(SILICOAT project) allows a good efficiency in inhibiting the
silica
toxic
ity, and the preliminary results obtained in an ongoing project (SILIFE)
suggest that the
developed dry method to coat quartz surface is also very promising
. The development of both coating
technologies (wet and a dry) should allow these coating technologi
es to be applied to a high variety of
industrial activities in which quartz is processed. For this reason, a lot of end
-users of quartz powders will
be potentially benefited from a reduced risk associated to the exposure to RCS. [-]
Description
International Conference Energy, Environment and Material Systems (EEMS 2017)
Is part of
E3S Web of Conferences (2017), v. 19Investigation project
1) SILICOAT project (FP7/2007 -2013) and 2) SILIFE project (LIFE14 ENV/ES/00238) .Rights
info:eu-repo/semantics/openAccess
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