Efficient and Selective N‐Methylation of Nitroarenes under Mild Reaction Conditions
Impacte
Scholar |
Altres documents de l'autoria: Pedrajas Gual, Elena; Sorribes, Iván; Guillamón, Eva; Junge, Henrik; Beller, matthias; Llusar, Rosa
Metadades
Mostra el registre complet de l'elementcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7013
comunitat-uji-handle3:10234/8638
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INVESTIGACIONMetadades
Títol
Efficient and Selective N‐Methylation of Nitroarenes under Mild Reaction ConditionsAutoria
Data de publicació
2017Editor
WileyISSN
0947-6539; 1521-3765Cita bibliogràfica
PEDRAJAS, Elena, et al. Efficient and Selective N‐Methylation of Nitroarenes under Mild Reaction Conditions. Chemistry–A European Journal, 2017, vol. 23, no 53, p. 13205-13212.Tipus de document
info:eu-repo/semantics/articleVersió de l'editorial
https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201702783Versió
info:eu-repo/semantics/acceptedVersionParaules clau / Matèries
Resum
Herein, we report a straightforward protocol for the preparation of N,N‐dimethylated amines from readily available nitro starting materials using formic acid as a renewable C1 source and silanes as reducing agents. ... [+]
Herein, we report a straightforward protocol for the preparation of N,N‐dimethylated amines from readily available nitro starting materials using formic acid as a renewable C1 source and silanes as reducing agents. This tandem process is efficiently accomplished in the presence of a cubane‐type Mo3PtS4 catalyst. For the preparation of the novel [Mo3Pt(PPh3)S4Cl3(dmen)3]+ (3+) (dmen: N,N′‐dimethylethylenediamine) compound we have followed a [3+1] building block strategy starting from the trinuclear [Mo3S4Cl3(dmen)3]+ (1+) and Pt(PPh3)4 (2) complexes. The heterobimetallic 3+ cation preserves the main structural features of its 1+ cluster precursor. Interestingly, this catalytic protocol operates at room temperature with high chemoselectivity when the 3+ catalyst co‐exists with its trinuclear 1+ precursor. N‐heterocyclic arenes, double bonds, ketones, cyanides and ester functional groups are well retained after N‐methylation of the corresponding functionalized nitroarenes. In addition, benzylic‐type as well as aliphatic nitro compounds can also be methylated following this protocol. [-]
Publicat a
Chemistry–A European Journal, 2017, vol. 23, no 53Proyecto de investigación
Spanish Ministerio de Economía y Competitividad: Grant CTQ2015‐65207‐P), Generalitat Valenciana: PrometeoII/2014/022) , Universitat Jaume I: UJI‐A2016‐05Drets d'accés
Copyright © John Wiley & Sons, Inc.
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info:eu-repo/semantics/openAccess
http://rightsstatements.org/vocab/InC/1.0/
info:eu-repo/semantics/openAccess
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