Modulation of Irisin and Physical Activity on Executive Functions in Obesity and Morbid obesity
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Other documents of the author: Fagundo, Ana B.; Jiménez-Murcia, Susana; Giner-Bartolomé, Cristina; Agüera, Zaida; Sauchelli, Sarah; Pardo, Marta; Crujeiras, Ana B.; Granero, Roser; Baños, Rosa Maria; Botella, Cristina; De la Torre, J. M.; Fernández-Real, José Manuel; Fernández García, José Carlos; Frühbeck, Gema; Rodríguez, Amaia; Mallorquí Bagué, Núria; Tárrega, Salomé; Tinahones Madueño, Francisco Javier; Rodríguez, Roser; Ortega, Francisco J.; Menchón, José Manuel; Casanueva, Felipe F.; Fernández Aranda, Fernando
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comunitat-uji-handle2:10234/8033
comunitat-uji-handle3:10234/8636
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INVESTIGACIONMetadata
Title
Modulation of Irisin and Physical Activity on Executive Functions in Obesity and Morbid obesityAuthor (s)
Date
2016-08-01Publisher
MacmillanBibliographic citation
FAGUNDO, Ana B.; JIMÉNEZ MURCIA, Susana, GINER-BARTOLOMÉ, Cristina; AGÜERA, Zaida; SAUCHELLI, Sarah; PARDO, Marta; CRUJEIRAS, Ana B.; GRANERO, Roser; BAÑOS RIVERA, Rosa María; BOTELLA ARBONA, Cristina; DE LA TORRE, J. M.; FERNÁNDEZ-REAL, José Manuel; FERNÁNDEZ GARCÍA, José Carlos; FRÜBECK, Gema; RODRÍGUEZ, Amaia; MALLORQUÍ BAGUÉ, Núria; TÁRREGA, Salomé; TINAHONES MADUEÑO, Francisco Javier; RODRÍGUEZ, Roser; ORTEGA, Francisco J.; MENCHÓN, José Manuel; CASANUEVA, Felipe F.; FERNÁNDEZ ARANDA, Fernando. Modulation of Irisin and Physical Activity on Executive Functions in Obesity and Morbid obesity. Scientific reports (2016), v. 6, pp. 1-10Type
info:eu-repo/semantics/articlePublisher version
http://www.nature.com/articles/srep30820Version
info:eu-repo/semantics/publishedVersionSubject
Abstract
Whether the executive profile is different between obesity (OB) and morbid obesity (MO) remains
unclear. Recent evidence suggests that physical activity (PA) can act as a cognitive enhancer. Irisin is a
recently ... [+]
Whether the executive profile is different between obesity (OB) and morbid obesity (MO) remains
unclear. Recent evidence suggests that physical activity (PA) can act as a cognitive enhancer. Irisin is a
recently discovered hormone associated with some of the positive effects of PA. The objective of the
study was to investigate the executive profile in OB and MO, and to explore the role of PA and irisin. 114
participants were included (21 OB, 44 MO and 49 healthy controls-HC) in the study and assessed with
the Wisconsin Card Sorting Test, Stroop Color and Word Test, and Iowa Gambling Task. All participants
were female, aged between 18 and 60 years. Results showed a similar dysfunctional profile on decision
making in OB and MO compared with HC. Thus, no specific neuropsychological profiles between OB and
MO can be clearly observed in our sample. However, a negative correlation was found between irisin
and executive functioning. These results demonstrate a specific executive profile in OB and a relevant
and negative modulation of irisin on executive functioning. Although irisin might be a promising target
for the treatment of obesity, its effects on cognition might be considered when thinking about its
therapeutic use. [-]
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