Highly sensitive and ultrafast read mapping for RNA-seq analysis
Visualitza/
Impacte
Scholar |
Altres documents de l'autoria: Barrachina Mir, Sergio; Castillo Catalán, María Isabel; Martínez Pérez, Héctor; Medina, Ignacio; Tárraga, Joaquín; Quintana-Orti, Enrique S.; Dopazo, Joaquín; Salavert Torres, José; Blanquer Espert, Ignacio; Paschall, J.; Hernández-García, V.
Metadades
Mostra el registre complet de l'elementcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/7036
comunitat-uji-handle3:10234/8620
comunitat-uji-handle4:
INVESTIGACIONMetadades
Títol
Highly sensitive and ultrafast read mapping for RNA-seq analysisAutoria
Data de publicació
2016Editor
Oxford University PressISSN
1340-2838; 1756-1663Cita bibliogràfica
I. Medina, J. Tárraga, H. Martínez, S. Barrachina, M. I. Castillo, J. Paschall, J. Salavert-Torres, I. Blanquer-Espert, V. Hernández-García, E. S. Quintana-Ortí, and J. Dopazo. Highly sensitive and ultrafast read mapping for RNA-seq analysis DNA Res first published online January 5, 2016 doi:10.1093/dnares/dsv039Tipus de document
info:eu-repo/semantics/articleVersió de l'editorial
http://dnaresearch.oxfordjournals.org/content/early/2016/01/05/dnares.dsv039.ful ...Paraules clau / Matèries
Resum
As sequencing technologies progress, the amount of data produced grows exponentially, shifting
the bottleneck of discovery towards the data analysis phase. In particular, currently available mapping
solutions for ... [+]
As sequencing technologies progress, the amount of data produced grows exponentially, shifting
the bottleneck of discovery towards the data analysis phase. In particular, currently available mapping
solutions for RNA-seq leave room for improvement in terms of sensitivity and performance, hindering
an efficient analysis of transcriptomes by massive sequencing. Here, we present an
innovative approach that combines re-engineering, optimization and parallelization. This solution results
in a significant increase of mapping sensitivity over a wide range of read lengths and substantial
shorter runtimes when compared with current RNA-seq mapping methods available. [-]
Drets d'accés
info:eu-repo/semantics/openAccess
Apareix a les col.leccions
- ICC_Articles [414]
Els següents fitxers sobre la llicència estan associats a aquest element: