Bilingualism and dementia: neural mechanisms and implications for cognitive reserve
Metadata
Show full item recordcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/29747
comunitat-uji-handle3:10234/162756
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TESISMetadata
Title
Bilingualism and dementia: neural mechanisms and implications for cognitive reserveAuthor (s)
Director
Ávila Rivera, César; Costumero Ramos, VíctorDoctoral Studies
Programa de Doctorat en PsicologiaResponsible entity
Universitat Jaume I. Escola de DoctoratDate of defense
2022-05-18Description
Compendi d'articles, Doctorat internacional
Publisher
Universitat Jaume ISubject
Keywords
Pages
188 p.;Abstract
Multiple studies have found that bilinguals show the first symptoms of dementia later than monolinguals. Therefore, it is hypothesized that bilingualism could protect against dementia, but the neural bases of this ... [+]
Multiple studies have found that bilinguals show the first symptoms of dementia later than monolinguals. Therefore, it is hypothesized that bilingualism could protect against dementia, but the neural bases of this protective effect are still unclear. In the works included in this thesis, we studied the neural mechanisms of bilingualism and dementia, and its implications for cognitive reserve, obtaining magnetic resonance images of bilingual and monolingual patients in different stages of Alzheimer’s disease (AD) and of healthy participants. We found that the neural bases of bilingualism’s protection against dementia could be the use of alternative brain circuits as a mechanism of compensation, in the presence of more structural atrophy in fibers and regions related to AD pathology, resulting in similar levels of cognitive impairment. This protection seems to start in prodromal AD stages and be maintained longitudinally until the disease starts. [-]
Rights
L'accés als continguts d'aquesta tesi queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons: http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess