Bilingualism and dementia: neural mechanisms and implications for cognitive reserve
Metadatos
Mostrar el registro completo del ítemcomunitat-uji-handle:10234/9
comunitat-uji-handle2:10234/29747
comunitat-uji-handle3:10234/162756
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TESISMetadatos
Título
Bilingualism and dementia: neural mechanisms and implications for cognitive reserveAutoría
Director/a
Ávila Rivera, César; Costumero Ramos, VíctorPrograma de Doctorado
Programa de Doctorat en PsicologiaÓrgano responsable
Universitat Jaume I. Escola de DoctoratFecha de defensa
2022-05-18Descripción
Compendi d'articles, Doctorat internacional
Editor
Universitat Jaume IPalabras clave
Área de conocimiento
Páginas
188 p.;Resumen
Multiple studies have found that bilinguals show the first symptoms of dementia later than monolinguals. Therefore, it is hypothesized that bilingualism could protect against dementia, but the neural bases of this ... [+]
Multiple studies have found that bilinguals show the first symptoms of dementia later than monolinguals. Therefore, it is hypothesized that bilingualism could protect against dementia, but the neural bases of this protective effect are still unclear. In the works included in this thesis, we studied the neural mechanisms of bilingualism and dementia, and its implications for cognitive reserve, obtaining magnetic resonance images of bilingual and monolingual patients in different stages of Alzheimer’s disease (AD) and of healthy participants. We found that the neural bases of bilingualism’s protection against dementia could be the use of alternative brain circuits as a mechanism of compensation, in the presence of more structural atrophy in fibers and regions related to AD pathology, resulting in similar levels of cognitive impairment. This protection seems to start in prodromal AD stages and be maintained longitudinally until the disease starts. [-]
Derechos de acceso
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info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess