Listar UJI: Investigación por autoría "a085da90-56bb-4772-849e-338cf9a04083"
Mostrando ítems 1-3 de 3
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Adolescent binge‐ethanol accelerates cognitive impairment and β‐amyloid production and dysregulates endocannabinoid signaling in the hippocampus of APP/PSE mice
Ledesma, Juan Carlos; Rodriguez-Arias, Marta; Gavito, Ana Luisa; Sánchez-Pérez, Ana María; Viña, J.; Medina-Vera, Dina; Rodríguez de Fonseca, Fernando; Miñarro, Josse Wiley (2020)Previous research in rodents suggests that the long‐term neurobehavioral disturbances induced by chronic ethanol (EtOH) exposure could be due to endocannabinoid system (ECS) alterations. Moreover, ECS failure has been ... -
Overexpression of glucose 6 phosphate dehydrogenase preserves mouse pancreatic beta cells function until late in life
De la Rosa, Adrián; Gomez-Cabrera , Mari Carmen; Vinue, Angela; Gonzalez-Navarro, Herminia; Sanchez-Andres, Juan V.; Viña, J. Elsevier (2021-01)NAD(P)H donates electrons for reductive biosynthesis and antioxidant defense across all forms of life. Glucose-6- phosphate dehydrogenase (G6PD) is a critical enzyme to provide NADPH. G6PD deficiency is present in more than ... -
Targeting Alzheimer's disease with multimodal polypeptide-based nanoconjugates
DURO-CASTANO, AROA; Borras, Consuelo; Herranz-Pérez, Vicente; Blanco-Gandia, M.Carmen; Conejos-Sanchez, Inmaculada; Armiñán, Ana; Mas Bargues, Cristina; Ingles, Marta; Miñarro, Josse; Rodriguez-Arias, Marta; García-Verdugo, Jose Manuel; Viña, J.; Vicent, Maria J. AAAS (American Association for the Advancement of Science) (2021-03-26)Alzheimer’s disease (AD), the most prevalent form of dementia, remains incurable mainly due to our failings in the search for effective pharmacological strategies. Here, we describe the development of targeted multimodal ...