Listar UJI: Investigación por autoría "4d7599ae-ff73-4ff2-8f8b-1b39d56ab6a4"
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Genetic and Chemical Modifiers Of A CUG Toxicity Model in Drosophila
Artero, Ruben D.; Álvarez Abril, María Carmen; Vicente Crespo, Marta; García Alcover, Irma; García López, Amparo; Monferrer Sales, Lidón Public Library of Science (PLoS) (2008)Non-coding CUG repeat expansions interfere with the activity of human Muscleblind-like (MBNL) proteins contributing to myotonic dystrophy 1 (DM1). To understand this toxic RNA gain-of-function mechanism we developed a ...