Stereoselective synthesis of a C1-C18 fragment of amphidinolides G and H
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INVESTIGACIONMetadatos
Título
Stereoselective synthesis of a C1-C18 fragment of amphidinolides G and HAutoría
Fecha de publicación
2013-04Editor
ElsevierCita bibliográfica
GARCÍA‐FORTANET, Jorge, et al. Stereoselective synthesis of a C1−C18 fragment of amphidinolides G and H . Tetrahedron , 2013, 69.15: 3192-3196Tipo de documento
info:eu-repo/semantics/articleVersión de la editorial
http://www.sciencedirect.com/science/article/pii/S0040402013002883Palabras clave / Materias
Resumen
A stereoselective synthesis of a C1–C18 segment of the structure of the cytotoxic macrolides amphidinolides G and H is reported. The target compound was retrosynthetically disconnected into three fragments. In the ... [+]
A stereoselective synthesis of a C1–C18 segment of the structure of the cytotoxic macrolides amphidinolides G and H is reported. The target compound was retrosynthetically disconnected into three fragments. In the synthetic sense, connection of the fragments was made by means of a Stille coupling and a Julia–Kocienski olefination. Precursors from the chiral pool were used as the starting materials. [-]
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Tetrahedron Volume 69, Issue 15, 15 April 2013Derechos de acceso
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