ListarQUIO_Articles por tema "peptides"
Mostrando ítems 1-7 de 7
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Effect of Hyaluronic Acid on the Self-Assembly of a Dipeptide-Based Supramolecular Gel
Wiley (2023-10-02)The combination of polymers and low molecular weight (LMW) compounds is a powerful approach to prepare new supramolecular materials. Here we prepare two-component hydrogels made by a well-known and biologically active ... -
Mechanistic Insight into the Lability of the Benzyloxycarbonyl (Z) Group inN-Protected Peptides under Mild Basic Conditions
Wiley Online Library (2014)The unexpected lability of Z protecting group under mild basic conditions at room temperature is explained by a mechanism based on anchimeric assistance. It is found that the vicinal amide group stabilizes the tetrahedral ... -
Morphology Diversity of L‐Phenylalanine‐Based Short Peptide Supramolecular Aggregates and Hydrogels
Wiley (2018-08)Supramolecular aggregates and hydrogels of diverse morphologies can be obtained by replacing the widely studied aromatic N‐capping of phenylalanine derivatives by long alkyl chains. Simple changes in chain length and number ... -
Pseudopeptidic host adaptation in peptide recognition unveiled by ion mobility mass spectrometry
Royal Society of Chemistry (2022-12-07)Complexation of the glutamic–tyrosine–glutamic tripeptide (EYE) with a series of pseudopeptidic cages has been thoroughly investigated using different analytical techniques. The stoichiometry and affinities of the ... -
Supramolecular protection from the enzymatic tyrosine phosphorylation in a polypeptide
Royal Society of Chemistry (2016-05)Here we report two new artificial pseudopeptidic cages that bind the EYE peptide epitope in pure water at physiological pH (as studied by fluorescence and NMR spectroscopies). The supramolecular complexation of the Tyr ... -
Tetrapeptidic Molecular Hydrogels: Self-assembly and Co-aggregation with Amyloid Fragment Aβ1-40
WILEY-VCH Verlag GmbH & Co. KGaA (2014-01)A new family of isomeric tetrapeptides containing aromatic and polar amino acid residues that are able to form molecular hydrogels following a smooth change in pH is described. The hydrogels have been studied by spectroscopic ... -
Towards Supramolecular Catalysis with Small Self-assembled Peptides
Wiley-VCH Verlag (2015-04)Self-assembly of small peptides offers unique opportunities for the bottom-up construction of supramolecular catalysts that aim to emulate the efficiency and selectivity of natural enzymes. Small, information-rich, simple ...