ListarQUIO_Articles por tema "IL-6"

Mostrando ítems 1-3 de 3

    • openAccess   Aryl azoles based scaffolds for disrupting tumor microenvironment 

      Pla López, Alberto; Martinez-Colomina, Paula; Cañada-García, Laura; Fuertes-Monge, Laura; Orellana-Palacios, Jose C.; Valderrama-Martínez, Alejandro; Pérez Sosa, Marikena; Carda, Miguel; Falomir, Eva Elsevier (2023-11-15)
      Thirty-nine aryl azoles, thirteen triazoles and twenty-seven tetrazoles, have been synthetized and biologically evaluated to determine their activity as tumor microenvironment disruptors. Antiproliferative studies have ...

    • openAccess   Styryl carbamate backbones for the discovery of TME-disrupting agents 

      Bou Puerto, Amelia; Carda, Miguel; Falomir, Eva Elsevier (2024)
      Twenty-one styryl carbamates have been designed, synthetized and characterized by their physical properties. Afterwards, their potential activity as tumor microenvironment disruptors has been evaluated. First, antiproliferative ...

    • openAccess   Synthesis and Biological Evaluation of Potential Oncoimmunomodulator Agents 

      Gil-Edo, Raquel; ESPEJO, SARA; Falomir, Eva; Carda, Miguel MDPI (2023-01-30)
      Fourteen triazole-scaffold derivatives were synthetized and biologically evaluated as potential oncoimmunomodultator agents by targeting both PD-L1 and c-Myc. First, the antiproliferative activity of these molecules on the ...