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Design and synthesis of pironetin analogues with simplified structure and study of their interactions with microtubules
Marco, J. Alberto; García Pla, Jorge; Carda, Miguel; Murga, Juan; Falomir, Eva; Trigili, Chiara; Notararigo, Sara; Díaz, J. Fernando; Barasoain, Isabel Elsevier (2011-05)The preparation of a series of pironetin analogues with simplified structure is described. Their cytotoxic activity and their interactions with tubulin have been investigated. It has been found that, while less active than ...