Listar QUIO_Articles por autoría "d0349304-8892-433a-9a43-56187583bd87"
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Arylureas derived from colchicine: Enhancement of colchicine oncogene downregulation activity
Blasco, Víctor; Cuñat, Ana Carmen; Sanz-Cervera, Juan F.; Marco, J. Alberto; Falomir, Eva; Murga, Juan; Carda, Miguel Elsevier (2018-04-25)Our efforts to get therapeutically useful colchicine derivatives for the treatment of cancer have led us to synthetize and biologically evaluate twenty-seven N,N′-disubstituted ureas containing a colchicine moiety and an ... -
Synthesis and biological evaluation of cyclic derivatives of combretastatin A-4 containing group 14 elements
Blasco, Víctor; Murga, Juan; Falomir, Eva; Carda, Miguel; Royo, Santiago; Cuñat, Ana Carmen; Sanz-Cervera, Juan F.; Marco, J. Alberto Royal Society of Chemistry (2018)Several tricyclic compounds inspired by the structure of combretastatin A-4 and bearing group 14 elements have been synthesized by homocoupling lithiated aryl fragments followed by ring-closing metathesis. These tricyclic ...