ListarQFA_Articles por tema "hyperconjugation"

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    • openAccess   Loss of Hyperconjugative Effects Drives Hydride Transfer during Dihydrofolate Reductase Catalysis 

      Angelastro, Antonio; Ruiz-Pernía, José Javier; Tuñón, Iñaki; Moliner, Vicent; Luk, Louis Y. P.; Allemann, Rudolf K. American Chemical Society (2019-09-23)
      Hydride transfer is widespread in nature and has an essential role in applied research. However, the mechanisms of how this transformation occurs in living organisms remain a matter of vigorous debate. Here, we examined ...