ListarQFA_Articles por tema "β-Adrenoceptor antagonists"
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Analysis of basic drugs by liquid chromatography with environmentally friendly mobile phases in pharmaceutical formulations
Elsevier (2017)Basic drugs are positively charged in the usual working pH (2–8) in reversed-phase liquid chromatography. This gives rise to a strong association with the residual ionized silanols in conventional silica-based stationary ... -
Effect of buffer nature and concentration on the chromatographic performance of basic compounds in the absence and presence of 1-hexyl-3-methylimidazolium chloride
Elsevier (2019-07-02)In reversed-phase liquid chromatography, the performance for basic compounds is affected by the interaction of the protonated (cationic) species with the anionic free silanols on the alkyl-bonded stationary phases. Using ...